Testing Data
(Human skeletal muscle myocytes showing moderate nuclear and faint cytoplasmic staining using MBS600390.)
Mouse anti-Human NP-5 Monoclonal Antibody | anti-LOC100009136 antibody
NP-5 (Alpha Defensin 5, Defensin 5, DEF5, Defensin alpha 5, Defensin alpha 5 Paneth Cell-specific, Defensin alpha 5 Preproprotein, DEFA5, HD5, HD-5, HNP5, HNP-5, MGC129728)
Gene Names
LOC100009136; CS-6; NP-5
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, Immunofluorescence
Purity
PurifiedPurified
Synonyms
NP-5; Monoclonal Antibody; NP-5 (Alpha Defensin 5; Defensin 5; DEF5; Defensin alpha 5; Defensin alpha 5 Paneth Cell-specific; Defensin alpha 5 Preproprotein; DEFA5; HD5; HD-5; HNP5; HNP-5; MGC129728); Anti -NP-5 (Alpha Defensin 5; anti-LOC100009136 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
9A8
Specificity
Recognizes human HD5 at ~12kD. No crossreactivity is observed with HD6, lysozyme or sPLA2.
Purity/Purification
Purified
Purified
Purified
Form/Format
Supplied as a liquid in Tris-glycine, 150mM sodium chloride, 0.05% sodium azide.
Applicable Applications for anti-LOC100009136 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
Suitable for use in Immunofluorescence, Western Blot and Immunohistochemistry.
Dilution: Immunohistochemistry (FFPE): 5-10ug/ml
Dilution: Immunohistochemistry (FFPE): 5-10ug/ml
Immunogen
Full-length proHD5 protein [Swiss-Prot# Q01523]. The propeptide is the full-length protein. In the mature form it is cleaved at residue 63 (alanine). Cellular Localization: Secreted.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Testing Data
(Human skeletal muscle myocytes showing moderate nuclear and faint cytoplasmic staining using MBS600390.)
Testing Data
(Human skeletal muscle myocytes showing moderate nuclear and faint cytoplasmic staining using MBS600390.)
Related Product Information for anti-LOC100009136 antibody
Human neutrophil alpha-defensins (also designated HNPs) are small, cationic, cysteine-rich antimicrobial proteins that play important roles in innate immunity against infectious microbes such as bacteria, fungi and enveloped viruses. Alpha-defensins are synthesized as inactive precursors and are activated by proteolytic cleavage by MMP-7. In the mature form, NP-5 is cleaved at residue 63 (alanine). Paneth cells in small intestinal crypts secrete the alpha-defensins, which are also termed cryptidins in mice. Alpha-defensins 5 and 6 probably contribute to innate defense of the GI mucosal surface by protecting against microbial invasion in states of intestinal inflammation.
Product Categories/Family for anti-LOC100009136 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
10,122 Da
NCBI Official Full Name
neutrophil antibiotic peptide NP-5
NCBI Official Symbol
LOC100009136
NCBI Official Synonym Symbols
CS-6; NP-5
NCBI Protein Information
neutrophil antibiotic peptide NP-5; defensin np-5; corticostatin CS-6; microbicidal peptide NP-5
UniProt Protein Name
Neutrophil antibiotic peptide NP-5
UniProt Entry Name
DEF6_RABIT
Uniprot Description
Function: Microbicidal activity.
Subcellular location: Secreted.
Sequence similarities: Belongs to the alpha-defensin family.
Similar Products
Product Notes
The LOC100009136 (Catalog #AAA600390) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The NP-5 (Alpha Defensin 5, Defensin 5, DEF5, Defensin alpha 5, Defensin alpha 5 Paneth Cell-specific, Defensin alpha 5 Preproprotein, DEFA5, HD5, HD-5, HNP5, HNP-5, MGC129728) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NP-5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). Suitable for use in Immunofluorescence, Western Blot and Immunohistochemistry. Dilution: Immunohistochemistry (FFPE): 5-10ug/ml. Researchers should empirically determine the suitability of the LOC100009136 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NP-5, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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