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Immunohistochemistry (IHC) (Immunohistochemistry of NOSTRIN in mouse kidney tissue with NOSTRIN antibody at 5 ug/ml.)

Rabbit NOSTRIN Polyclonal Antibody | anti-NOSTRIN antibody

Anti-NOSTRIN Antibody (C-Terminus) IHC-plus

Gene Names
Nostrin; Daip2; mDaIP2
Reactivity
Mouse, Rat, Human
Applications
Immunohistochemistry, Immunofluorescence, Western Blot, ELISA
Purity
Immunoaffinity purified
Synonyms
NOSTRIN; Polyclonal Antibody; Anti-NOSTRIN Antibody (C-Terminus) IHC-plus; Rabbit Polyclonal to Human NOSTRIN; Human NOSTRIN; BM247 homolog; ENOS traffic inducer; ENOS-trafficking inducer; DaIP2; anti-NOSTRIN antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse, Rat, Human
Clonality
Polyclonal
Specificity
NOSTRIN antibody is human, mouse and rat reactive. At least four isoforms are known to exist; this antibody will detect all four isoforms.
Purity/Purification
Immunoaffinity purified
Form/Format
PBS, 0.02% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
506
Applicable Applications for anti-NOSTRIN antibody
Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
Application Notes
IF (20 ug/ml)
IHC-P (10 ug/ml)
WB (1 - 2 ug/ml)
Immunogen
NOSTRIN antibody was raised against nOSTRIN antibody was raised against a 17 amino acid peptide near the carboxy terminus of human NOSTRIN.
Immunogen Description
NOSTRIN antibody was raised against a 17 amino acid peptide near the carboxy terminus of human NOSTRIN.
Immunogen Type
Synthetic peptide
Antigen Modification
C-Terminus
Target Species
Human
Preparation and Storage
Long term: -20 degree C
Short term: 4 degree C
Avoid repeat freeze-thaw cycles

Immunohistochemistry (IHC)

(Immunohistochemistry of NOSTRIN in mouse kidney tissue with NOSTRIN antibody at 5 ug/ml.)

Immunohistochemistry (IHC) (Immunohistochemistry of NOSTRIN in mouse kidney tissue with NOSTRIN antibody at 5 ug/ml.)

Immunohistochemistry (IHC)

(Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (IHC) (Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunofluorescence (IF)

(Immunofluorescence of NOSTRIN in mouse kidney tissue with NOSTRIN antibody at 20 ug/ml.)

Immunofluorescence (IF) (Immunofluorescence of NOSTRIN in mouse kidney tissue with NOSTRIN antibody at 20 ug/ml.)
Related Product Information for anti-NOSTRIN antibody
NOSTRIN Antibody, BM247 homolog Antibody, ENOS traffic inducer Antibody, ENOS-trafficking inducer Antibody, DaIP2 Antibody Description: Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
57,673 Da
NCBI Official Full Name
nostrin
NCBI Official Synonym Full Names
nitric oxide synthase trafficker
NCBI Official Symbol
Nostrin
NCBI Official Synonym Symbols
Daip2; mDaIP2
NCBI Protein Information
nostrin
UniProt Protein Name
Nostrin
Protein Family
UniProt Gene Name
Nostrin
UniProt Synonym Gene Names
Daip2; Dab2-interacting protein 2
UniProt Entry Name
NOSTN_MOUSE

Uniprot Description

NOSTRIN: Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Cellular Component: cytoplasm; cytoplasmic vesicle; membrane; nucleus; plasma membrane

Molecular Function: DNA binding; protein binding

Biological Process: endocytosis; negative regulation of transcription, DNA-dependent

Research Articles on NOSTRIN

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Product Notes

The NOSTRIN nostrin (Catalog #AAA2400055) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-NOSTRIN Antibody (C-Terminus) IHC-plus reacts with Mouse, Rat, Human and may cross-react with other species as described in the data sheet. AAA Biotech's NOSTRIN can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), Western Blot (WB), ELISA (EIA). IF (20 ug/ml) IHC-P (10 ug/ml) WB (1 - 2 ug/ml). Researchers should empirically determine the suitability of the NOSTRIN nostrin for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NOSTRIN, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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