Western Blot (WB)
(hCG_1646420 Antibody (Center) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the hCG_1646420 antibody detected the hCG_1646420 protein (arrow).)
Rabbit anti-Human hCG_1646420 Polyclonal Antibody | anti-CLDN25 antibody
hCG_1646420 Antibody (Center)
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
hCG_1646420; Polyclonal Antibody; hCG_1646420 Antibody (Center); Putative claudin-25; CLDN25; anti-CLDN25 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This hCG_1646420 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-128 amino acids from the Central region of human hCG_1646420.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
99-128
Sequence Length
229
Applicable Applications for anti-CLDN25 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(hCG_1646420 Antibody (Center) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the hCG_1646420 antibody detected the hCG_1646420 protein (arrow).)
Western Blot (WB)
(hCG_1646420 Antibody (Center) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the hCG_1646420 antibody detected the hCG_1646420 protein (arrow).)
Related Product Information for anti-CLDN25 antibody
This gene encodes a member of the claudin family. Claudins
are integral membrane proteins and components of tight junction
strands. Tight junction strands serve as a physical barrier to
prevent solutes and water from passing freely through the
paracellular space between epithelial or endothelial cell sheets,
and also play critical roles in maintaining cell polarity and
signal transductions.
are integral membrane proteins and components of tight junction
strands. Tight junction strands serve as a physical barrier to
prevent solutes and water from passing freely through the
paracellular space between epithelial or endothelial cell sheets,
and also play critical roles in maintaining cell polarity and
signal transductions.
Product Categories/Family for anti-CLDN25 antibody
References
Lal-Nag, M., et al. Genome Biol. 10 (8), 235 (2009) :
Krause, G., et al. Biochim. Biophys. Acta 1778(3):631-645(2008)
Katoh, M., et al. Int. J. Mol. Med. 11(6):683-689(2003)
Venter, J.C., et al. Science 291(5507):1304-1351(2001)
Krause, G., et al. Biochim. Biophys. Acta 1778(3):631-645(2008)
Katoh, M., et al. Int. J. Mol. Med. 11(6):683-689(2003)
Venter, J.C., et al. Science 291(5507):1304-1351(2001)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
25394
NCBI Official Full Name
putative claudin-25
NCBI Official Synonym Full Names
claudin 25
NCBI Official Symbol
CLDN25
NCBI Protein Information
putative claudin-25
UniProt Protein Name
Putative claudin-25
Protein Family
UniProt Gene Name
CLDN25
UniProt Entry Name
CLD25_HUMAN
NCBI Description
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. [provided by RefSeq, Jun 2010]
Uniprot Description
hCG_1646420: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. Belongs to the claudin family.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 11q23.2
Cellular Component: tight junction; integral to membrane; plasma membrane
Molecular Function: structural molecule activity
Similar Products
Product Notes
The CLDN25 cldn25 (Catalog #AAA9214270) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 99-128. The hCG_1646420 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's hCG_1646420 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the CLDN25 cldn25 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "hCG_1646420, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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