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Western Blot (WB) (Western Blot analysis of extracts of various cells, using NOSIP antibody.)

Rabbit anti-Human NOSIP Polyclonal Antibody | anti-NOSIP antibody

NOSIP Polyclonal Antibody

Gene Names
NOSIP; CGI-25
Reactivity
Human
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
NOSIP; Polyclonal Antibody; NOSIP Polyclonal Antibody; CGI-25; Nitric oxide synthase-interacting protein; anti-NOSIP antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
NOSIP polyclonal antibody detects endogenous levels of NOSIP protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
301
Applicable Applications for anti-NOSIP antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant protein of human NOSIP.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot analysis of extracts of various cells, using NOSIP antibody.)

Western Blot (WB) (Western Blot analysis of extracts of various cells, using NOSIP antibody.)
Related Product Information for anti-NOSIP antibody
Endothelial nitric oxide synthase (eNOS) interacting protein (NOSIP) is a modulator of eNOS activity. eNOS is an important nitric oxide (NO)-generating enzyme of the vasculature that is regulated by interactions with caveolin-1, Ca2+-calmodulin, HSP 90 and NOSIP. NOSIP modulates this activity by promoting the translocation of eNOS from the plasma membrane to intracellular sites, which in turn inhibits NO synthesis. NOSIP is involved in controlling airway and vascular diameter, synthesis of NO in ciliated epithelia and mucosal secretion, and is an important protein for mucociliary and bronchial function. NOSIP is highly expressed in endothelial cells and vascularized tissue.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 33kDa
NCBI Official Full Name
nitric oxide synthase-interacting protein isoform 1
NCBI Official Synonym Full Names
nitric oxide synthase interacting protein
NCBI Official Symbol
NOSIP
NCBI Official Synonym Symbols
CGI-25
NCBI Protein Information
nitric oxide synthase-interacting protein
UniProt Protein Name
Nitric oxide synthase-interacting protein
UniProt Gene Name
NOSIP
UniProt Entry Name
NOSIP_HUMAN

NCBI Description

The protein encoded by this gene may modulate the activity and localization of nitric oxide synthase (endothelial and neuronal) and thus nitric oxide production. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2012]

Research Articles on NOSIP

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Product Notes

The NOSIP nosip (Catalog #AAA3008960) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NOSIP Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NOSIP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the NOSIP nosip for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NOSIP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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