Western Blot (WB)
(Western Blot (WB) analysis of EYA1/4 polyclonal antibody at 1:500 dilutionLane1:A549 whole cell lysateLane2:H9C2 whole cell lysate)
Rabbit anti-Human, Rat EYA1/4 Polyclonal Antibody | anti-EYA1/4 antibody
EYA1/4 Polyclonal Antibody
Gene Names
EYA1; BOP; BOR; BOS1; OFC1
Reactivity
Human, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
EYA1/4; Polyclonal Antibody; EYA1/4 Polyclonal Antibody; Eyes absent homolog 1; EYA1; Eyes absent homolog 4; EYA4; anti-EYA1/4 antibody
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
EYA1/4 polyclonal antibody detects endogenous levels of EYA1/4 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
592
Applicable Applications for anti-EYA1/4 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
A synthetic peptide corresponding to residues in Human EYA1/4
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot (WB) analysis of EYA1/4 polyclonal antibody at 1:500 dilutionLane1:A549 whole cell lysateLane2:H9C2 whole cell lysate)
Western Blot (WB)
(Western Blot (WB) analysis of EYA1/4 polyclonal antibody at 1:500 dilutionLane1:A549 whole cell lysateLane2:H9C2 whole cell lysate)
Related Product Information for anti-EYA1/4 antibody
A gene on chromosome 8q13.3 encodes EYA1 (eyes absent), a protein with 16 exons. EYA1 is one of four members of the eyes absent family. A 271 amino acid domain at the carboxyl terminal is highly conserved amongst the members of the eyes absent family, while the PST (proline-serine-threonin)-rich amino terminal is highly divergent. EYA is expressed in flexor tendons and the developing central nervous system, kidney, eye and ear. EYA1 acts a transcriptional activator in connective tissue patterning through its PST domain, which functions as a transactivation domain. EYA1 plays a critical role in the development of the inner ear and kidney. EYA is involved in early inductive signaling, acting upstream of GDNF. EYA1 has been implicated in the autosomal dominant disorders branchio-oto-renal (BOR) syndrome and branhio-oto (BO) syndrome.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
~ 70kDa
NCBI Official Full Name
eyes absent homolog 1 isoform 1
NCBI Official Synonym Full Names
EYA transcriptional coactivator and phosphatase 1
NCBI Official Symbol
EYA1
NCBI Official Synonym Symbols
BOP; BOR; BOS1; OFC1
NCBI Protein Information
eyes absent homolog 1
UniProt Protein Name
Eyes absent homolog 1
UniProt Gene Name
EYA1
UniProt Entry Name
EYA1_HUMAN
NCBI Description
This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may play a role in the developing kidney, branchial arches, eye, and ear. Mutations of this gene have been associated with branchiootorenal dysplasia syndrome, branchiootic syndrome, and sporadic cases of congenital cataracts and ocular anterior segment anomalies. A similar protein in mice can act as a transcriptional activator. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Dec 2013]
Research Articles on EYA1/4
Similar Products
Product Notes
The EYA1/4 eya1 (Catalog #AAA3006986) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EYA1/4 Polyclonal Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's EYA1/4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the EYA1/4 eya1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EYA1/4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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