Rabbit anti-Human NOMO1 Polyclonal Antibody | anti-NOMO1 antibody

NOMO1, Phosphorylated (Ser1205) (Nodal Modulator 1, pM5, PM5) (PE)

Cat. Num. AAA6490285

• Gene Names: NOMO1; PM5; Nomo
• Reactivity: Human
• Applications: Dot Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: NOMO1; Polyclonal Antibody; Phosphorylated (Ser1205) (Nodal Modulator 1; pM5; PM5) (PE); anti-NOMO1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human NOMO1 when phosphorylated at Ser1205.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

• Applicable Applications for anti-NOMO1 antibody: FLISA, Dot Blot (DB)
• Application Notes: FLISA: 1:1,000; Dot Blot: 1:500; Applications are based on unconjugated antibody.
• Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser1205 of human NOMO1 (KLH).
• Conjugate: PE
• Antigen Modification: Phosphorylated
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Dot Blot (DB)

(Dot blot analysis of anti-Phospho-NOMO1-pS1205 Antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.)

Product Categories/Family for anti-NOMO1 antibody

Antibodies; Proteins

References

1. Blackshaw, S., PLoS Biol. 2(9), E247 (2004).

NCBI and Uniprot Product Information

• NCBI GI #: 51944953
• NCBI GeneID: 23420
• NCBI Accession #: NP_055102
• NCBI GenBank Nucleotide #: NM_014287.4
• UniProt Accession #: Q15155; P69849
• Molecular Weight: 134
• NCBI Official Full Name: nodal modulator 1
• NCBI Official Synonym Full Names: NODAL modulator 1
• NCBI Official Symbol: NOMO1
• NCBI Official Synonym Symbols: PM5; Nomo
• NCBI Protein Information: nodal modulator 1
• UniProt Protein Name: Nodal modulator 1
• Protein Family: Nodal modulator
• UniProt Gene Name: NOMO1
• UniProt Synonym Gene Names: PM5
• UniProt Entry Name: NOMO1_HUMAN

NCBI Description

This gene encodes a protein originally thought to be related to the collagenase gene family. This gene is one of three highly similar genes in a region of duplication located on the p arm of chromosome 16. These three genes encode closely related proteins that may have the same function. The protein encoded by one of these genes has been identified as part of a protein complex that participates in the Nodal signaling pathway during vertebrate development. Mutations in ABCC6, which is located nearby, rather than mutations in this gene are associated with pseudoxanthoma elasticum (PXE). [provided by RefSeq, Jul 2008]

Uniprot Description

NOMO1: May antagonize Nodal signaling.

Protein type: Membrane protein, integral; Cell surface

Chromosomal Location of Human Ortholog: 16p13.11

Cellular Component: membrane; integral to membrane

Molecular Function: carbohydrate binding