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Rabbit anti-Human, Mouse NOL3 Polyclonal Antibody | anti-NOL3 antibody

NOL3 Rabbit pAb

Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry, Immunofluorescence
Purity
Affinity Purified
Synonyms
NOL3; Polyclonal Antibody; NOL3 Rabbit pAb; ARC; FCM; MYP; NOP; NOP30; anti-NOL3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purified
Form/Format
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Sequence Length
219
Applicable Applications for anti-NOL3 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:200
IF: 1:50-1:200
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-208 of human NOL3 (NP_003937.1).
Cellular Localization
Cytoplasm, Membrane, Mitochondrion, Nucleus, Sarcoplasmic Reticulum
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Related Product Information for anti-NOL3 antibody
Isoform 1: May be involved in RNA splicing.

NCBI and Uniprot Product Information

NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
28kDa
NCBI Official Full Name
nucleolar protein 3 isoform Nop30
UniProt Protein Name
Nucleolar protein 3
Protein Family
UniProt Gene Name
NOL3
UniProt Synonym Gene Names
ARC; NOP; Myp; Nop30
UniProt Entry Name
NOL3_HUMAN

Uniprot Description

Function: Isoform 1 may be involved in RNA splicing.Isoform 2 may inhibit apoptosis.

Subunit structure: Interacts with TFPT

By similarity. Isoform 1 oligomerizes and binds to SFRS9/SRp30C and also interacts with NPM1. Isoform 2 binds CASP2/caspase-2 and CASP8/caspase-8 and inhibits caspase-8 activity. Ref.1

Subcellular location: Isoform 1: Nucleus › nucleolus. Isoform 2: Cytoplasm.

Tissue specificity: Highly expressed in heart and skeletal muscle. Detected at low levels in placenta, liver, kidney and pancreas.

Sequence similarities: Contains 1 CARD domain.

Similar Products

Product Notes

The NOL3 nol3 (Catalog #AAA8549334) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NOL3 Rabbit pAb reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's NOL3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). WB: 1:500-1:2000 IHC: 1:50-1:200 IF: 1:50-1:200. Researchers should empirically determine the suitability of the NOL3 nol3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NOL3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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