Western Blot (WB)
(Host: RabbitTarget Name: NOL3Sample Tissue: Human HCT15 Whole Cell lysatesAntibody Dilution: 1ug/ml)
Rabbit anti-Human NOL3 Polyclonal Antibody | anti-NOL3 antibody
NOL3 Antibody - middle region
Western Blot (WB)
(Host: RabbitTarget Name: NOL3Sample Tissue: Human HCT15 Whole Cell lysatesAntibody Dilution: 1ug/ml)
Western Blot (WB)
(Host: RabbitTarget Name: NOL3Sample Tissue: Human HCT15 Whole Cell lysatesAntibody Dilution: 1ug/ml)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an anti-apoptotic protein that has been shown to down-regulate the enzyme activities of caspase 2, caspase 8 and tumor protein p53. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Uniprot Description
Function: Isoform 1 may be involved in RNA splicing.Isoform 2 may inhibit apoptosis.
Subunit structure: Interacts with TFPT
By similarity. Isoform 1 oligomerizes and binds to SFRS9/SRp30C and also interacts with NPM1. Isoform 2 binds CASP2/caspase-2 and CASP8/caspase-8 and inhibits caspase-8 activity. Ref.1
Subcellular location: Isoform 1: Nucleus › nucleolus. Isoform 2: Cytoplasm.
Tissue specificity: Highly expressed in heart and skeletal muscle. Detected at low levels in placenta, liver, kidney and pancreas.
Sequence similarities: Contains 1 CARD domain.
Research Articles on NOL3
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Product Notes
The NOL3 nol3 (Catalog #AAA3223185) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NOL3 Antibody - middle region reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NOL3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the NOL3 nol3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: RSRSQSQSWN PRLKQNQSRN WSQNRTQSPS PTSRKGTSPK IPEGQSSDRR. It is sometimes possible for the material contained within the vial of "NOL3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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