Western Blot (WB)
(Western Blot analysis of OPRL1 expression in transfected 293T cell line byMBS629638. Lane 1: OPRL1 transfected lysate (40.70kD). Lane 2: Non-transfected lysate.)
Rabbit anti-Human Nociceptin Receptor Polyclonal Antibody | anti-OPRL1 antibody
Nociceptin Receptor (Kappa-type 3 Opioid Receptor, KOR-3, Orphanin FQ Receptor, OPRL1, OOR, ORL1) (Biotin)
Gene Names
OPRL1; OOR; ORL1; KOR-3; NOCIR
Reactivity
Human
Applications
Western Blot
Purity
Purified
Synonyms
Nociceptin Receptor; Polyclonal Antibody; Nociceptin Receptor (Kappa-type 3 Opioid Receptor; KOR-3; Orphanin FQ Receptor; OPRL1; OOR; ORL1) (Biotin); anti-OPRL1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human OPRL1.
Purity/Purification
Purified
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Applicable Applications for anti-OPRL1 antibody
Western Blot (WB)
Application Notes
For maximum recovery of product, 11c7entrifuge the original vial after thawing and prior to removing the cap.
Applications are based on unconjugated antibody.
Applications are based on unconjugated antibody.
Immunogen
Full-length human protein corresponding to aa1370 from human OPRL1 (NP_000904.1).
Immunogen Sequence
MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIRRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAILRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALACKTSETVPRPA
Conjugate
Biotin
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(Western Blot analysis of OPRL1 expression in transfected 293T cell line byMBS629638. Lane 1: OPRL1 transfected lysate (40.70kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of OPRL1 expression in transfected 293T cell line byMBS629638. Lane 1: OPRL1 transfected lysate (40.70kD). Lane 2: Non-transfected lysate.)
Related Product Information for anti-OPRL1 antibody
The protein encoded by this gene is a G protein-coupled receptor whose expression can be induced by phytohemagglutinin. The encoded integral membrane protein is a receptor for the 17aa neuropeptide nociceptin/orphanin FQ. This gene may be involved in the regulation of numerous brain activities, particularly instinctive and emotional behaviors. A promoter for this gene also functions as a promoter for another gene, regulator of G-protein signalling 19 (RGS19), located on the opposite strand. Two transcript variants encoding the same protein have been found for this gene.
Product Categories/Family for anti-OPRL1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
40,693 Da
NCBI Official Full Name
nociceptin receptor
NCBI Official Synonym Full Names
opiate receptor-like 1
NCBI Official Symbol
OPRL1
NCBI Official Synonym Symbols
OOR; ORL1; KOR-3; NOCIR
NCBI Protein Information
nociceptin receptor; orphanin FQ receptor; kappa-type 3 opioid receptor; kappa3-related opioid receptor
UniProt Protein Name
Nociceptin receptor
Protein Family
UniProt Gene Name
OPRL1
UniProt Synonym Gene Names
OOR; ORL1; KOR-3
UniProt Entry Name
OPRX_HUMAN
Uniprot Description
KOR-3: Receptor for the neuropeptide nociceptin/orphanin FQ. Has a potential role in modulating a number of brain functions, including instinctive behaviors and emotions. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1
Chromosomal Location of Human Ortholog: 20q13.33
Cellular Component: neuron projection; integral to plasma membrane; cytoplasmic membrane-bound vesicle; plasma membrane
Molecular Function: G-protein coupled receptor activity; neuropeptide binding; protein binding; nociceptin/orphanin-FQ receptor activity
Biological Process: synaptic transmission; elevation of cytosolic calcium ion concentration; neuropeptide signaling pathway; sensory perception; behavior; G-protein signaling, adenylate cyclase inhibiting pathway; sensory perception of pain
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Product Notes
The OPRL1 oprl1 (Catalog #AAA6490233) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Nociceptin Receptor (Kappa-type 3 Opioid Receptor, KOR-3, Orphanin FQ Receptor, OPRL1, OOR, ORL1) (Biotin) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Nociceptin Receptor can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). For maximum recovery of product, 11c7entrifuge the original vial after thawing and prior to removing the cap. Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the OPRL1 oprl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Nociceptin Receptor, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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