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Rabbit anti-Human NMUR2 Polyclonal Antibody | anti-NMUR2 antibody

NMUR2 antibody

Gene Names
NMUR2; FM4; FM-4; TGR1; NMU2R; TGR-1; NMU-R2
Reactivity
Human
Applications
Immunohistochemistry
Purity
NMUR2 antibody was purified by affinity chromatography.
Synonyms
NMUR2; Polyclonal Antibody; NMUR2 antibody; Polyclonal NMUR2; Anti-NMUR2; neuromedin u receptor 2; G protein-coupled receptor fm4; tgr-1; SNORF62; neuromedin u receptor-type 2; NMUR -2; nmu-r2; nmu2r; neuromedin S receptor; NMUR 2; anti-NMUR2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
Human
Purity/Purification
NMUR2 antibody was purified by affinity chromatography.
Form/Format
Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1% NaN3.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
415
Applicable Applications for anti-NMUR2 antibody
Immunohistochemistry (IHC) Paraffin
Application Notes
IHC-P: 20 ug/ml
Biological Significance
The neuromedin U receptors are two G-protein coupled receptors which bind the neuropeptide hormones neuromedin U and neuromedin S. There are two subtypes of the neuromedin U receptor, each encoded by a separate gene. Neuromedin U is an agonist at both the NMU1 and NMU2 subtypes, while neuromedin S is selective for NMU2, and is a more potent agonist at this subtype than neuromedin U. Several other peptide and non-peptide ligands are also available for the NMU receptors.
Biohazard Information
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.
Immunogen
NMUR2 antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -70 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-NMUR2 antibody
Rabbit polyclonal NMUR2 antibody
Product Categories/Family for anti-NMUR2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
47,696 Da
NCBI Official Full Name
neuromedin-U receptor 2
NCBI Official Synonym Full Names
neuromedin U receptor 2
NCBI Official Symbol
NMUR2
NCBI Official Synonym Symbols
FM4; FM-4; TGR1; NMU2R; TGR-1; NMU-R2
NCBI Protein Information
neuromedin-U receptor 2
UniProt Protein Name
Neuromedin-U receptor 2
Protein Family
UniProt Gene Name
NMUR2
UniProt Synonym Gene Names
NMU2R; TGR1; NMU-R2
UniProt Entry Name
NMUR2_HUMAN

NCBI Description

This gene encodes a protein from the G-protein coupled receptor 1 family. This protein is a receptor for neuromedin U, which is a neuropeptide that is widely distributed in the gut and central nervous system. This receptor plays an important role in the regulation of food intake and body weight. [provided by RefSeq, Jul 2008]

Uniprot Description

NMUR2: Receptor for the neuromedin-U and neuromedin-S neuropeptides. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 5q33.1

Cellular Component: plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity; intracellular calcium activated chloride channel activity; GTP binding; neuromedin U receptor activity; neuromedin U binding

Biological Process: grooming behavior; regulation of smooth muscle contraction; inositol phosphate-mediated signaling; central nervous system development; calcium-mediated signaling; chloride transport; response to pain; arachidonic acid secretion; reduction of food intake in response to dietary excess; elevation of cytosolic calcium ion concentration; cell-cell signaling; neuropeptide signaling pathway; calcium ion transport; calcium-dependent phospholipase A2 activation; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); feeding behavior

Research Articles on NMUR2

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Product Notes

The NMUR2 nmur2 (Catalog #AAA535520) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NMUR2 antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NMUR2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin. IHC-P: 20 ug/ml. Researchers should empirically determine the suitability of the NMUR2 nmur2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NMUR2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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