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Immunohistochemistry (IHC) (Anti-NMUR2 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Rabbit NMUR2 Polyclonal Antibody | anti-NMUR2 antibody

Rabbit Polyclonal to Human NMUR2

Gene Names
NMUR2; FM4; FM-4; TGR1; NMU2R; TGR-1; NMU-R2
Reactivity
Gibbon, Gorilla, Human
Predicted Reactivity: Monkey (at least 90% immunogen sequence identity)
Applications
Immunohistochemistry, ELISA
Purity
Immunoaffinity Purified
Synonyms
NMUR2; Polyclonal Antibody; Rabbit Polyclonal to Human NMUR2; Anti-NMUR2 Antibody (N-Terminus) IHC-plus; FM-4; FM4; Neuromedin-U receptor 2; TGR1; Neuromedin u receptor-type 2; TGR-1; Neuromedin U receptor 2; NMU-R2; NMU2R; Human NMUR2; anti-NMUR2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Gibbon, Gorilla, Human
Predicted Reactivity: Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Specificity
Human NMUR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
415
Applicable Applications for anti-NMUR2 antibody
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
Application Notes
ELISA, IHC-P (20 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib...
Target Species
Human
Immunogen Description
Synthetic 17 amino acid peptide from N-terminal extracellular domain of human NMUR2. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset (94%).
Immunogen Type
Synthetic peptide
Immunogen
NMUR2 antibody was raised against synthetic 17 amino acid peptide from N-terminal extracellular domain of human NMUR2. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset (94%).
Antigen Modification
N-Terminus
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C

Immunohistochemistry (IHC)

(Anti-NMUR2 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-NMUR2 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-NMUR2 antibody
Neuromedin U Receptor 2 is a Neuromedin Receptor. NMU2R may mediate the contractile activity of neuromedin U in the uterus.
Product Categories/Family for anti-NMUR2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
47,696 Da
NCBI Official Full Name
neuromedin-U receptor 2
NCBI Official Synonym Full Names
neuromedin U receptor 2
NCBI Official Symbol
NMUR2
NCBI Official Synonym Symbols
FM4; FM-4; TGR1; NMU2R; TGR-1; NMU-R2
NCBI Protein Information
neuromedin-U receptor 2; G-protein coupled receptor FM-4; G-protein coupled receptor TGR-1; growth hormone secretagogue receptor family, member 4
UniProt Protein Name
Neuromedin-U receptor 2
Protein Family
UniProt Gene Name
NMUR2
UniProt Synonym Gene Names
NMU2R; TGR1; NMU-R2
UniProt Entry Name
NMUR2_HUMAN

NCBI Description

This gene encodes a protein from the G-protein coupled receptor 1 family. This protein is a receptor for neuromedin U, which is a neuropeptide that is widely distributed in the gut and central nervous system. This receptor plays an important role in the regulation of food intake and body weight. [provided by RefSeq, Jul 2008]

Uniprot Description

NMUR2: Receptor for the neuromedin-U and neuromedin-S neuropeptides. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 5q33.1

Cellular Component: plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity; GTP binding; intracellular calcium activated chloride channel activity; neuromedin U receptor activity; neuromedin U binding

Biological Process: grooming behavior; regulation of smooth muscle contraction; inositol phosphate-mediated signaling; central nervous system development; calcium-mediated signaling; chloride transport; response to pain; arachidonic acid secretion; reduction of food intake in response to dietary excess; elevation of cytosolic calcium ion concentration; cell-cell signaling; neuropeptide signaling pathway; calcium ion transport; calcium-dependent phospholipase A2 activation; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); feeding behavior

Research Articles on NMUR2

Similar Products

Product Notes

The NMUR2 nmur2 (Catalog #AAA240932) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human NMUR2 reacts with Gibbon, Gorilla, Human Predicted Reactivity: Monkey (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's NMUR2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), ELISA (EIA). ELISA, IHC-P (20 ug/ml) Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib.. Researchers should empirically determine the suitability of the NMUR2 nmur2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NMUR2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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