Rabbit anti-Human NMUR2 Polyclonal Antibody | anti-NMUR2 antibody

NMUR2, NT (Neuromedin-U Receptor 2, NMU-R2, G-protein Coupled Receptor FM-4, G-protein Coupled Receptor TGR-1, NMU2R, TGR1)

Cat. Num. AAA647575

• Gene Names: NMUR2; FM4; FM-4; TGR1; NMU2R; TGR-1; NMU-R2
• Reactivity: Human
• Applications: Immunohistochemistry
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: NMUR2; Polyclonal Antibody; NT (Neuromedin-U Receptor 2; NMU-R2; G-protein Coupled Receptor FM-4; G-protein Coupled Receptor TGR-1; NMU2R; TGR1); Anti -NMUR2; anti-NMUR2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: Recognizes human NMUR2. Species sequence homology: mouse (47%) and rat (53%).
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a liquid in PBS, 0.1% sodium azide.

• Applicable Applications for anti-NMUR2 antibody: Immunohistochemistry (IHC)
• Application Notes: Suitable for use in Immunohistochemistry.; Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 20ug/ml
• Immunogen: Synthetic peptide corresponding to 17aa from N-terminal extracellular domain of human NMUR2.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunohistochemistry (IHC)

(Human Adrenal (formalin-fixed, paraffin-embedded) stained with NMUR2 antibody at 20ug/ml followed by biotinylated goat rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.)

Related Product Information for anti-NMUR2 antibody

Neuromedin U Receptor 2 is a Neuromedin Receptor. NMU2R may mediate the contractile activity of neuromedin U in the uterus.

Product Categories/Family for anti-NMUR2 antibody

Antibodies; Abs to G Protein Receptors

NCBI and Uniprot Product Information

• NCBI GI #: 170932505
• NCBI GeneID: 56923
• NCBI Accession #: NP_064552.3
• NCBI GenBank Nucleotide #: NM_020167.4
• UniProt Accession #: Q9GZQ4; Q7LC54; Q96AM5; Q9NRA6
• Molecular Weight: 47,696 Da
• NCBI Official Full Name: neuromedin-U receptor 2
• NCBI Official Synonym Full Names: neuromedin U receptor 2
• NCBI Official Symbol: NMUR2
• NCBI Official Synonym Symbols: FM4; FM-4; TGR1; NMU2R; TGR-1; NMU-R2
• NCBI Protein Information: neuromedin-U receptor 2; G-protein coupled receptor FM-4; G-protein coupled receptor TGR-1; growth hormone secretagogue receptor family, member 4
• UniProt Protein Name: Neuromedin-U receptor 2
• Protein Family: Neuromedin-U receptor
• UniProt Gene Name: NMUR2
• UniProt Synonym Gene Names: NMU2R; TGR1; NMU-R2
• UniProt Entry Name: NMUR2_HUMAN

NCBI Description

This gene encodes a protein from the G-protein coupled receptor 1 family. This protein is a receptor for neuromedin U, which is a neuropeptide that is widely distributed in the gut and central nervous system. This receptor plays an important role in the regulation of food intake and body weight. [provided by RefSeq, Jul 2008]

Uniprot Description

Function: Receptor for the neuromedin-U and neuromedin-S neuropeptides

By similarity. Ref.2

Subcellular location: Cell membrane; Multi-pass membrane protein.

Tissue specificity: Predominantly expressed in the CNS, particularly in the medulla oblongata, pontine reticular formation, spinal cord, and thalamus. High level in testis whereas lower levels are present in a variety of peripheral tissues including the gastrointestinal tract, genitourinary tract, liver, pancreas, adrenal gland, thyroid gland, lung, trachea, spleen and thymus. Ref.1 Ref.2 Ref.3 Ref.6

Sequence similarities: Belongs to the G-protein coupled receptor 1 family.

Caution: It is uncertain whether Met-1 or Met-4 is the initiator.

Sequence caution: The sequence BAB13721.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.