Rabbit NMUR1 GPR66 Polyclonal Antibody | anti-NMUR1 antibody
NMUR1 GPR66 Antibody FITC Conjugated
Gene Names
NMUR1; FM3; FM-3; GPC-R; GPR66; NMU1R; (FM-3)
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Flow Cytometry, Functional Assay
Purity
Purified by Protein A
Synonyms
NMUR1 GPR66; Polyclonal Antibody; NMUR1 GPR66 Antibody FITC Conjugated; FM-3; G protein-coupled receptor 66; G-protein coupled receptor 66; G-protein coupled receptor FM-3; GPR66; Growth hormone secretagogue receptor family Member 3; Neuromedin U Receptor 1; Neuromedin-U receptor 1; NMU-R1; NMUR1; NMUR1_HUMAN NMUR1 GPR66; anti-NMUR1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A
Form/Format
10mM Tris Buffered Saline containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Concentration
1mgml (varies by lot)
Applicable Applications for anti-NMUR1 antibody
Immunofluorescence (IF), Flow Cytometry (FC/FACS)
Application Notes
FC/FACS: 1:20-100
IF: 1:50-200
IF: 1:50-200
Conjugation
FITC
Excitation Emission
494nm 518nm
Immunogen
KLH conjugated synthetic peptide derived from human NMUR1
Preparation and Storage
Store at 4 degree C for 12 months.
Related Product Information for anti-NMUR1 antibody
Neuromedin U is a neuropeptide with high activity on smooth muscle. It is widely expressed in gastrointestinal systems and central nervous system (CNS). Peripheral activities of neuromedin U include smooth muscle stimulation, ion transport alterations in the gut and the regulation of local blood flow and adrenocortical function. Neuromedin U receptors 1 and 2 (NMUR1 and NMUR2) are multi-pass membrane proteins that belong to the G-protein coupled receptor 1 family of proteins. Both NMUR1 and NMUR2 act as receptors for the neuromedin U neuropeptide. NMUR1 is detected in peripheral organs, particularly in urogenital and gastrointestinal systems, with highest levels in testis. Its expression in CNS is low, but the protein has been detected in cerebellum, hippocampus, dorsal root ganglia and spinal cord. NMUR2 is predominantly detected in central nervous system with highest levels detected in medulla oblongata, spinal cord and thalamus. It may also be detected in testis but has low levels of expression in peripheral tissues.
Product Categories/Family for anti-NMUR1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
47,351 Da
NCBI Official Full Name
neuromedin-U receptor 1
NCBI Official Synonym Full Names
neuromedin U receptor 1
NCBI Official Symbol
NMUR1
NCBI Official Synonym Symbols
FM3; FM-3; GPC-R; GPR66; NMU1R; (FM-3)
NCBI Protein Information
neuromedin-U receptor 1; NMU-R1; G protein-coupled receptor 66; G-protein coupled receptor 66; G-protein coupled receptor FM-3
UniProt Protein Name
Neuromedin-U receptor 1
Protein Family
UniProt Gene Name
NMUR1
UniProt Synonym Gene Names
GPR66; NMU-R1
UniProt Entry Name
NMUR1_HUMAN
Uniprot Description
NMUR1: Receptor for the neuromedin-U and neuromedin-S neuropeptides. Belongs to the G-protein coupled receptor 1 family.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1
Chromosomal Location of Human Ortholog: 2q37.1
Cellular Component: integral to plasma membrane; plasma membrane; integral to membrane
Molecular Function: G-protein coupled receptor activity; neuropeptide receptor activity; neuromedin U receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway; inositol phosphate-mediated signaling; smooth muscle contraction; phospholipase C activation; neuropeptide signaling pathway; calcium ion transport; calcium-mediated signaling; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); chloride transport
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Product Notes
The NMUR1 nmur1 (Catalog #AAA9460368) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NMUR1 GPR66 Antibody FITC Conjugated reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NMUR1 GPR66 can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), Flow Cytometry (FC/FACS). FC/FACS: 1:20-100 IF: 1:50-200. Researchers should empirically determine the suitability of the NMUR1 nmur1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NMUR1 GPR66, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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