Western Blot (WB)
(NLN Antibody (Center) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the NLN antibody detected the NLN protein (arrow).)
Rabbit anti-Human NLN Polyclonal Antibody | anti-NLN antibody
NLN Antibody (Center)
Gene Names
NLN; MEP; MOP; AGTBP; EP24.16
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
NLN; Polyclonal Antibody; NLN Antibody (Center); Neurolysin; mitochondrial; Angiotensin-binding protein; Microsomal endopeptidase; MEP; Mitochondrial oligopeptidase M; Neurotensin endopeptidase; AGTBP; KIAA1226; anti-NLN antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This NLN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-240 amino acids from the Central region of human NLN.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
212-240
Sequence Length
704
Applicable Applications for anti-NLN antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(NLN Antibody (Center) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the NLN antibody detected the NLN protein (arrow).)
Western Blot (WB)
(NLN Antibody (Center) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the NLN antibody detected the NLN protein (arrow).)
Related Product Information for anti-NLN antibody
This gene encodes a member of the metallopeptidase M3
protein family that cleaves neurotensin at the Pro10-Tyr11 bond,
leading to the formation of neurotensin(1-10) and
neurotensin(11-13). The encoded protein is likely involved in the
termination of the neurotensinergic signal in the central nervous
system and in the gastrointestinal tract.
protein family that cleaves neurotensin at the Pro10-Tyr11 bond,
leading to the formation of neurotensin(1-10) and
neurotensin(11-13). The encoded protein is likely involved in the
termination of the neurotensinergic signal in the central nervous
system and in the gastrointestinal tract.
Product Categories/Family for anti-NLN antibody
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Lim, E.J., et al. J. Biol. Chem. 282(13):9722-9732(2007)
Norman, M.U., et al. Am. J. Physiol. Heart Circ. Physiol. 284 (6), H1978-H1984 (2003) :
Norman, M.U., et al. Am. J. Physiol. Heart Circ. Physiol. 284 (6), H1978-H1984 (2003) :
Garrido, P.A., et al. DNA Cell Biol. 18(4):323-331(1999)
Lim, E.J., et al. J. Biol. Chem. 282(13):9722-9732(2007)
Norman, M.U., et al. Am. J. Physiol. Heart Circ. Physiol. 284 (6), H1978-H1984 (2003) :
Norman, M.U., et al. Am. J. Physiol. Heart Circ. Physiol. 284 (6), H1978-H1984 (2003) :
Garrido, P.A., et al. DNA Cell Biol. 18(4):323-331(1999)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
80652
NCBI Official Full Name
neurolysin, mitochondrial
NCBI Official Synonym Full Names
neurolysin (metallopeptidase M3 family)
NCBI Official Symbol
NLN
NCBI Official Synonym Symbols
MEP; MOP; AGTBP; EP24.16
NCBI Protein Information
neurolysin, mitochondrial
UniProt Protein Name
Neurolysin, mitochondrial
Protein Family
UniProt Gene Name
NLN
UniProt Synonym Gene Names
AGTBP; KIAA1226; MEP
UniProt Entry Name
NEUL_HUMAN
NCBI Description
This gene encodes a member of the metallopeptidase M3 protein family that cleaves neurotensin at the Pro10-Tyr11 bond, leading to the formation of neurotensin(1-10) and neurotensin(11-13). The encoded protein is likely involved in the termination of the neurotensinergic signal in the central nervous system and in the gastrointestinal tract.[provided by RefSeq, Jun 2010]
Uniprot Description
NLN: Hydrolyzes oligopeptides such as neurotensin, bradykinin and dynorphin A. Belongs to the peptidase M3 family.
Protein type: Protease; Mitochondrial; EC 3.4.24.16
Chromosomal Location of Human Ortholog: 5q12.3
Cellular Component: plasma membrane; mitochondrial intermembrane space
Molecular Function: metal ion binding; metalloendopeptidase activity; peptide binding
Biological Process: proteolysis
Research Articles on NLN
Similar Products
Product Notes
The NLN nln (Catalog #AAA9206435) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 212-240. The NLN Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NLN can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the NLN nln for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NLN, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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