Rabbit anti-Human NLN Polyclonal Antibody | anti-NLN antibody

NLN, ID (NLN, AGTBP, KIAA1226, Neurolysin, mitochondrial, Angiotensin-binding protein, Microsomal endopeptidase, Mitochondrial oligopeptidase M, Neurotensin endopeptidase) (Azide free) (HRP)

Cat. Num. AAA6325734

• Gene Names: NLN; MEP; MOP; AGTBP; EP24.16
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: NLN; Polyclonal Antibody; ID (NLN; AGTBP; KIAA1226; Neurolysin; mitochondrial; Angiotensin-binding protein; Microsomal endopeptidase; Mitochondrial oligopeptidase M; Neurotensin endopeptidase) (Azide free) (HRP); mitochondrial oligopeptidase M; Neurotensin endopeptidase; anti-NLN antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human NLN.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).

• Applicable Applications for anti-NLN antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 212-240 in the centrall region of human NLN, UniProt Accession #NP_065777.1; Q9BYT8.
• Conjugate: HRP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis in A2058 cell line lysates (35ug/lane) usingMBS6004952.This demonstrates the NLN antibody detected the NLN protein (arrow).)

Related Product Information for anti-NLN antibody

This gene encodes a member of the metallopeptidase M3 protein family that cleaves neurotensin at the Pro10-Tyr11 bond, leading to the formation of neurotensin(1-10) and neurotensin(11-13). The encoded protein is likely involved in the termination of the neurotensinergic signal in the central nervous system and in the gastrointestinal tract.

Product Categories/Family for anti-NLN antibody

Antibodies; Angiotensin(ogen)

References

1. Rose, J. Phd, et al. Mol. Med. (2010). 2. Lim, E.J., et al. J. Biol. Chem. 282(13):9722-9732 (2007). 3. Norman, M.U., et al. Am. J. Physiol. Heart Circ. Physiol. 284 (6), H1978-H1984 (2003). 4. Norman, M.U., et al. Am. J. Physiol. Heart Circ. Physiol. 284 (6), H1978-H1984 (2003). 5. Garrido, P.A., et al. DNA Cell Biol. 18(4):323-331 (1999).

NCBI and Uniprot Product Information

• NCBI GI #: 14149738
• NCBI GeneID: 57486
• NCBI Accession #: NP_065777.1
• NCBI GenBank Nucleotide #: NM_020726.4
• UniProt Accession #: Q9BYT8; Q9ULJ4
• Molecular Weight: 80,652 Da
• NCBI Official Full Name: neurolysin, mitochondrial
• NCBI Official Synonym Full Names: neurolysin (metallopeptidase M3 family)
• NCBI Official Symbol: NLN
• NCBI Official Synonym Symbols: MEP; MOP; AGTBP; EP24.16
• NCBI Protein Information: neurolysin, mitochondrial; angiotensin binding protein; angiotensin-binding protein; endopeptidase 24.16; microsomal endopeptidase; mitochondrial oligopeptidase M; neurotensin endopeptidase
• UniProt Protein Name: Neurolysin, mitochondrial
• Protein Family: Neurolysin
• UniProt Gene Name: NLN
• UniProt Synonym Gene Names: AGTBP; KIAA1226; MEP
• UniProt Entry Name: NEUL_HUMAN