Rabbit anti-Human NKIRAS2 Polyclonal Antibody | anti-NKIRAS2 antibody
NKIRAS2 Antibody, FITC conjugated
Gene Names
NKIRAS2; KBRAS2; kappaB-Ras2
Reactivity
Human
Applications
ELISA
Purity
>95%, Protein G Purified
Synonyms
NKIRAS2; Polyclonal Antibody; NKIRAS2 Antibody; FITC conjugated; NF-kappa-B inhibitor-interacting Ras-like protein 2; KBRAS2; I-kappa-B-interacting Ras-like protein 2; Kappa B-Ras protein 2; KappaB-Ras2; anti-NKIRAS2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G Purified
Sequence Length
191
Applicable Applications for anti-NKIRAS2 antibody
ELISA (EIA)
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
FITC
Immunogen
Recombinant human NF-kappa-B inhibitor-interacting Ras-like protein 2 protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-10528
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Related Product Information for anti-NKIRAS2 antibody
Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB (By similarity).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
10,770 Da
NCBI Official Full Name
NF-kappa-B inhibitor-interacting Ras-like protein 2 isoform a
NCBI Official Synonym Full Names
NFKB inhibitor interacting Ras-like 2
NCBI Official Symbol
NKIRAS2
NCBI Official Synonym Symbols
KBRAS2; kappaB-Ras2
NCBI Protein Information
NF-kappa-B inhibitor-interacting Ras-like protein 2
UniProt Protein Name
NF-kappa-B inhibitor-interacting Ras-like protein 2
Protein Family
UniProt Gene Name
NKIRAS2
UniProt Synonym Gene Names
KBRAS2; Kappa B-Ras protein 2; KappaB-Ras2
UniProt Entry Name
KBRS2_HUMAN
Uniprot Description
NKIRAS2: Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF- kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB. Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: G protein, monomeric, Ras; G protein; G protein, monomeric
Chromosomal Location of Human Ortholog: 17q21.2
Cellular Component: cytoplasm; membrane
Molecular Function: GTP binding; GTPase activity
Biological Process: I-kappaB kinase/NF-kappaB cascade; small GTPase mediated signal transduction
Research Articles on NKIRAS2
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Product Notes
The NKIRAS2 nkiras2 (Catalog #AAA1493088) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NKIRAS2 Antibody, FITC conjugated reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NKIRAS2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the NKIRAS2 nkiras2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NKIRAS2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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