Rabbit anti-Human NFIP2 Polyclonal Antibody | anti-NFIP2 antibody
NFIP2 Polyclonal Antibody
Gene Names
NDFIP2; N4WBP5A
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
NFIP2; Polyclonal Antibody; NFIP2 Polyclonal Antibody; NEDD4 family-interacting protein 2; NEDD4 WW domain-binding protein 5A; Putative MAPK-activating protein PM04/PM05/PM06/PM07; Putative NF-kappa-B-activating protein 413; NDFIP2; KIAA1165; N4WBP5A; anti-NFIP2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Sequence Length
336
Applicable Applications for anti-NFIP2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-2000
ELISA: 1:5000-20000
ELISA: 1:5000-20000
Preparation and Storage
Store at-20 degree C for 1 year.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
36
NCBI Official Full Name
NEDD4 family-interacting protein 2 isoform 1
NCBI Official Synonym Full Names
Nedd4 family interacting protein 2
NCBI Official Symbol
NDFIP2
NCBI Official Synonym Symbols
N4WBP5A
NCBI Protein Information
NEDD4 family-interacting protein 2
UniProt Protein Name
NEDD4 family-interacting protein 2
UniProt Gene Name
NDFIP2
UniProt Synonym Gene Names
KIAA1165; N4WBP5A
Uniprot Description
Activates HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1 and WWP2, and consequently modulates the stability of their targets. As a result, may control many cellular processes. Recruits ITCH, NEDD4 and SMURF2 to endosomal membranes. Negatively regulates KCNH2 potassium channel activity by decreasing its cell-surface expression and interfering with channel maturation through recruitment of NEDD4L to the Golgi apparatus and multivesicular body where it mediates KCNH2 degradation (PubMed:26363003). May modulate EGFR signaling. Together with NDFIP1, limits the cytokine signaling and expansion of effector Th2 T-cells by promoting degradation of JAK1, probably by ITCH- and NEDD4L-mediated ubiquitination ().
Research Articles on NFIP2
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Product Notes
The NFIP2 ndfip2 (Catalog #AAA8531176) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NFIP2 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NFIP2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-2000 ELISA: 1:5000-20000. Researchers should empirically determine the suitability of the NFIP2 ndfip2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NFIP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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