Western Blot (WB)
(Western blot analysis of NEU1 Antibody (Center) in MDA-MB231 cell line lysates (35ug/lane). NEU1 (arrow) was detected using the purified Pab.)
Rabbit anti-Human NEU1 Polyclonal Antibody | anti-OXT antibody
NEU1 Antibody (Center)
Western Blot (WB)
(Western blot analysis of NEU1 Antibody (Center) in MDA-MB231 cell line lysates (35ug/lane). NEU1 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of NEU1 Antibody (Center) in MDA-MB231 cell line lysates (35ug/lane). NEU1 (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(NEU1 Antibody (Center) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the NEU1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(NEU1 Antibody (Center) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the NEU1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Flow Cytometry (FC/FACS)
(NEU1 Antibody (Center) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(NEU1 Antibody (Center) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Ivell, R., et al. Endocrinology 127(6):2990-2996(1990)
Wood, S.P., et al. Science 232(4750):633-636(1986)
Sausville, E., et al. J. Biol. Chem. 260(18):10236-10241(1985)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a precursor protein that is processed to produce oxytocin and neurophysin I. Oxytocin is a posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. [provided by RefSeq, Dec 2013]
Uniprot Description
OXT: Neurophysin 1 specifically binds oxytocin. Belongs to the vasopressin/oxytocin family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 20p13
Cellular Component: extracellular space; extracellular region; terminal button; secretory granule
Molecular Function: oxytocin receptor binding; neurohypophyseal hormone activity
Biological Process: response to peptide hormone stimulus; response to cAMP; male mating behavior; heart development; drinking behavior; response to glucocorticoid stimulus; positive regulation of female receptivity; female pregnancy; signal transduction; response to estradiol stimulus; positive regulation of synaptic transmission; elevation of cytosolic calcium ion concentration; hyperosmotic salinity response; negative regulation of blood pressure; response to electrical stimulus; grooming behavior; response to food; response to retinoic acid; maternal behavior; regulation of heart rate; eating behavior; response to amphetamine; social behavior; sleep; response to cocaine; response to ether; memory; positive regulation of ossification; response to sucrose stimulus; positive regulation of synaptogenesis; positive regulation of prostaglandin secretion; response to activity; regulation of sensory perception of pain; sperm ejaculation; response to progesterone stimulus; positive regulation of blood pressure
Research Articles on OXT
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Product Notes
The OXT oxt (Catalog #AAA9203702) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 11-40. The NEU1 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NEU1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). WB~~1:1000. Researchers should empirically determine the suitability of the OXT oxt for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NEU1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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