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Rabbit anti-Human NESTIN Polyclonal Antibody | anti-NESTIN antibody

NESTIN

Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Purified By Antigen Affinity Column
Synonyms
NESTIN; Polyclonal Antibody; Nbla00170; NES; anti-NESTIN antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified By Antigen Affinity Column
Form/Format
Already dissolved in sterile H2O with 1% BSA and 0.02% NaN3 and 50% Glycerol.
Sequence Length
1621
Applicable Applications for anti-NESTIN antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:20,000-80,000
IHC: 1:100-500
Immunogen
A peptide corresponding to the C terminal residues of human NESTIN protein.
Cellular Localization
Intermediate Filament
References
Kodet O, Dvorankova B, Krejci E, et al. Cultivation-dependent plasticity of melanoma phenotype. Tumour Biol. 34 (6):3345-3355 (2013)

NCBI and Uniprot Product Information

NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
nestin
UniProt Protein Name
Nestin
Protein Family
UniProt Gene Name
NES
UniProt Entry Name
NEST_HUMAN

Uniprot Description

nestin: an intermediate filament protein. It is expressed predominantly in stem cells of the central nervous system in the neural tube. Upon terminal neural differentiation, nestin is downregulated and replaced by neurofilaments.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 1q23.1

Cellular Component: intermediate filament cytoskeleton; cytoplasm; intermediate filament

Molecular Function: intermediate filament binding; structural molecule activity

Biological Process: positive regulation of intermediate filament depolymerization; central nervous system development; negative regulation of catalytic activity; cell projection morphogenesis; brain development; negative regulation of neuron apoptosis; negative regulation of protein binding; G2/M transition of mitotic cell cycle; embryonic camera-type eye development

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Product Notes

The NESTIN nes (Catalog #AAA8560311) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NESTIN reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NESTIN can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). ELISA: 1:20,000-80,000 IHC: 1:100-500. Researchers should empirically determine the suitability of the NESTIN nes for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NESTIN, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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