Rabbit anti-Rat Nephroblastoma Overexpressed Gene Polyclonal Antibody | anti-NOV antibody
Polyclonal Antibody to Nephroblastoma Overexpressed Gene (NOV)
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- AVPGE CCEKWTCGSE EKGTLGGLAL PAYRPEATVG VELSDSSINC IEQTTEWSAC SKSCGMGLST RVTNRNLQCE MVKQTRLCMV RPCEQEPGEA TDMKGKKCLR TKKSLKSIHL QFKNCTSLYT YKPRFCGICS DGRCCTPFNT KTIQVEFQCL PGQIIKKPVM VIGTCTCHSN CPQNNEAFLQ ELELKTSRGE
Immunohistochemistry: 5-20ug/mL;1:25-100
Immunocytochemistry: 5-20ug/mL;1:25-100
Optimal working dilutions must be determined by end user.
Western Blot (WB)
(Western Blot: Sample: Rat Serum; Primary Ab: 2ug/ml Rabbit Anti-Rat NOV Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
NCBI and Uniprot Product Information
NCBI Description
acts as a growth factor for some cells and binds to a specific receptor; may also have growth suppressive effects [RGD, Feb 2006]
Uniprot Description
NOV: Immediate-early protein likely to play a role in cell growth regulation. Belongs to the CCN family. Expression is down-regulated by WT1. Interacts with FBLN1.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 7q32
Cellular Component: axon; cell soma; cytoplasm; dendrite; extracellular matrix; extracellular region; extracellular space; gap junction; intracellular membrane-bound organelle; proteinaceous extracellular matrix
Molecular Function: growth factor activity; heparin binding; insulin-like growth factor binding; integrin binding; Notch binding
Biological Process: angiogenesis; cell adhesion; cell adhesion mediated by integrin; cell-cell signaling; chondrocyte differentiation; negative regulation of cell growth; negative regulation of inflammatory response; negative regulation of insulin secretion; negative regulation of NF-kappaB import into nucleus; positive regulation of Notch signaling pathway; regulation of gene expression; signal transduction; smooth muscle cell migration; smooth muscle cell proliferation
Research Articles on NOV
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Product Notes
The NOV nov (Catalog #AAA2026207) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Nephroblastoma Overexpressed Gene (NOV) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Nephroblastoma Overexpressed Gene can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 0.2-2ug/mL;1:250-2500 Immunohistochemistry: 5-20ug/mL;1:25-100 Immunocytochemistry: 5-20ug/mL;1:25-100 Optimal working dilutions must be determined by end user. . Researchers should empirically determine the suitability of the NOV nov for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- AVPGE CCEKWTCGSE EKGTLGGLAL PAYRPEATVG VELSDSSINC IEQTTEWSAC SKSCGMGLST RVTNRNLQCE MVKQTRLCMV RPCEQEPGEA TDMKGKKCLR TKKSLKSIHL QFKNCTSLYT YKPRFCGICS DGRCCTPFNT KTIQVEFQCL PGQIIKKPVM VIGTCTCHSN CPQNNEAFLQ ELELKTSRGE. It is sometimes possible for the material contained within the vial of "Nephroblastoma Overexpressed Gene, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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