Western Blot (WB)
(Western Blot analysis of Jurkat, Raji and A431 cell, Mouse skeletal muscle tissue and NIH/3T3 cell using NDUFV2 Polyclonal Antibody at dilution of 1:250)
Rabbit NDUFV2 Polyclonal Antibody | anti-NDUFV2 antibody
NDUFV2 Polyclonal Antibody
Western Blot (WB)
(Western Blot analysis of Jurkat, Raji and A431 cell, Mouse skeletal muscle tissue and NIH/3T3 cell using NDUFV2 Polyclonal Antibody at dilution of 1:250)
Western Blot (WB)
(Western Blot analysis of Jurkat, Raji and A431 cell, Mouse skeletal muscle tissue and NIH/3T3 cell using NDUFV2 Polyclonal Antibody at dilution of 1:250)
NCBI and Uniprot Product Information
NCBI Description
The NADH-ubiquinone oxidoreductase complex (complex I) of the mitochondrial respiratory chain catalyzes the transfer of electrons from NADH to ubiquinone, and consists of at least 43 subunits. The complex is located in the inner mitochondrial membrane. This gene encodes the 24 kDa subunit of complex I, and is involved in electron transfer. Mutations in this gene are implicated in Parkinson's disease, bipolar disorder, schizophrenia, and have been found in one case of early onset hypertrophic cardiomyopathy and encephalopathy. A non-transcribed pseudogene of this locus is found on chromosome 19. [provided by RefSeq, Oct 2009]
Uniprot Description
NDUFV2: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I 24 kDa subunit family.
Protein type: Energy Metabolism - oxidative phosphorylation; EC 1.6.5.3; Oxidoreductase; Mitochondrial; EC 1.6.99.3
Chromosomal Location of Human Ortholog: 18p11.22
Cellular Component: mitochondrion; mitochondrial inner membrane; mitochondrial respiratory chain complex I
Molecular Function: 2 iron, 2 sulfur cluster binding; electron carrier activity; NADH dehydrogenase (ubiquinone) activity; metal ion binding
Biological Process: cardiac muscle development; cellular metabolic process; nervous system development; mitochondrial electron transport, NADH to ubiquinone
Disease: Mitochondrial Complex I Deficiency
Research Articles on NDUFV2
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Product Notes
The NDUFV2 ndufv2 (Catalog #AAA2522662) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NDUFV2 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NDUFV2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). WB: 1:200-1:1000. Researchers should empirically determine the suitability of the NDUFV2 ndufv2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NDUFV2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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