Rabbit anti-Human, Mouse NDUFB11 Polyclonal Antibody | anti-NDUFB11 antibody

NDUFB11 Rabbit pAb

Cat. Num. AAA4754536

• Gene Names: NDUFB11; ESSS; Np15; P17.3; NP17.3; CI-ESSS; LSDMCA3
• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot
• Purity: Affinity purified
• Synonyms: NDUFB11; Polyclonal Antibody; NDUFB11 Rabbit pAb; ESSS; Np15; P17.3; NP17.3; CI-ESSS; LSDMCA3; anti-NDUFB11 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Purity/Purification: Affinity purified
• Form/Format: -20 degree C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

• Applicable Applications for anti-NDUFB11 antibody: ELISA (EIA), Western Blot (WB)
• Application Notes: WB: 1:1000-1:5000
• Immunogen: Full length fusion protein
• Conjugation: Unconjugated
• Molecular Function: Complex 1 (also known as NADH dehydrogenase) of the electron transport chain (respiratory chain) is an enzymatic complex that catalyzes the transfer of electrons from NADH to ubiquinone. Free energy from the reaction is conserved in the transfer of protons into the intermembrane space to create an electrochemical proton gradient, a driving force for ATP synthesis. Complex 1 is a complicated, multi-protein, L-shaped complex composed of at least 45 different subunits and located in the mitochondrial inner membrane. NDUFB11 (NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11), also known as ESSS, Np15, Np17.3 (neuronal protein 17.3) or p17.3, is a hydrophobic transmembrane protein belonging to the Complex I NDUFB11 subunit family. Ubiquitously expressed, NDUFB11 localizes to the inner membrane of the mitochondrion and functions as an accessory subunit of Complex I. The cAMP-dependent phosphorylation of NDUFB11 is important for the regulation of Complex I activity.
• Modification: Unmodified
• Cell Position: Membrane, Mitochondrion, Mitochondrion inner membrane
• Preparation and Storage: Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Gel: 12%SDS-PAGE, Lysate: 40 ug, Lane 1-7: Hela, HEPG2, A431, K562 and 231 cell, Mouse liver tissue and Mouse brain tissue lysates, Primary antibody: 123630(NDUFB11 Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds)

Product Categories/Family for anti-NDUFB11 antibody

Primary antibody

NCBI and Uniprot Product Information

• NCBI GI #: 14715010
• NCBI GeneID: 54539
• UniProt Accession #: Q9NX14; Q5JRR3; Q5JRR4; Q6IAB6; Q8WZ96; Q9BXX9
• Molecular Weight: 18,364 Da
• NCBI Official Full Name: Homo sapiens NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa, mRNA
• NCBI Official Synonym Full Names: NADH:ubiquinone oxidoreductase subunit B11
• NCBI Official Symbol: NDUFB11
• NCBI Official Synonym Symbols: ESSS; Np15; P17.3; NP17.3; CI-ESSS; LSDMCA3
• NCBI Protein Information: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial
• UniProt Protein Name: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial
• Protein Family: NADH dehydrogenase
• UniProt Gene Name: NDUFB11
• UniProt Synonym Gene Names: CI-ESSS; Np17.3; p17.3
• UniProt Entry Name: NDUBB_HUMAN

NCBI Description

NDUFB11 is a component of mitochondrial complex I. Complex I catalyzes the first step in the electron transport chain, the transfer of 2 electrons from NADH to ubiquinone, coupled to the translocation of 4 protons across the membrane (Carroll et al., 2002 [PubMed 12381726]).[supplied by OMIM, Feb 2009]