Rabbit NDRG1 Polyclonal Antibody | anti-NDRG1 antibody

NDRG1 Polyclonal Antibody

Cat. Num. AAA3008197

• Gene Names: NDRG1; GC4; RTP; DRG1; NDR1; NMSL; TDD5; CAP43; CMT4D; DRG-1; HMSNL; RIT42; TARG1; PROXY1
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunofluorescence
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: NDRG1; Polyclonal Antibody; NDRG1 Polyclonal Antibody; Protein NDRG1; Differentiation-related gene 1 protein; DRG-1; N-myc downstream-regulated gene 1 protein; Nickel-specific induction protein Cap43; Reducing agents and tunicamycin-responsive protein; RTP; Rit42; CAP43; DRG1; anti-NDRG1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: NDRG1 polyclonal antibody detects endogenous levels of NDRG1 protein.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 394

• Applicable Applications for anti-NDRG1 antibody: Western Blot (WB), Immunofluorescence (IF)
• Application Notes: WB: 1:500-1:2000; IF: 1:50-1:200
• Immunogen: Recombinant full length Human NDRG1.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot analysis of NDRG1 polyclonal antibody)

Immunofluorescence (IF)

(Immunofluorescence analysis of MCF7 cells, using NDRG1 polyclonal antibody)

Related Product Information for anti-NDRG1 antibody

NDRG1 is ubiquitously expressed, but it is expressed most prominently in placental membranes and prostate, kidney, small intestine and ovary tissue. NDRG1 gene expression is induced by several compounds, including nickel, and produces a protein involved in stress responses, hormone responses, cell growth and differentiation.

NCBI and Uniprot Product Information

• NCBI GI #: 207028748
• NCBI GeneID: 10397
• NCBI Accession #: NP_001128714.1
• NCBI GenBank Nucleotide #: NP_001128714.1
• UniProt Accession #: Q92597
• Molecular Weight: ~ 48kDa
• NCBI Official Full Name: protein NDRG1 isoform 1
• NCBI Official Synonym Full Names: N-myc downstream regulated 1
• NCBI Official Symbol: NDRG1
• NCBI Official Synonym Symbols: GC4; RTP; DRG1; NDR1; NMSL; TDD5; CAP43; CMT4D; DRG-1; HMSNL; RIT42; TARG1; PROXY1
• NCBI Protein Information: protein NDRG1
• UniProt Protein Name: Protein NDRG1
• Protein Family: Protein
• UniProt Gene Name: NDRG1
• UniProt Synonym Gene Names: CAP43; DRG1; RTP; DRG-1; RTP
• UniProt Entry Name: NDRG1_HUMAN

NCBI Description

This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]