Rabbit NAT1 Polyclonal Antibody | anti-NAT1 antibody

NAT1 Antibody

Cat. Num. AAA9406197

• Gene Names: NAT1; AAC1; MNAT; NATI; NAT-1
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry
• Purity: Antibodies were purified by affinity purification using immunogen.
• Synonyms: NAT1; Polyclonal Antibody; NAT1 Antibody; AAC1; MNAT; NATI; NAT-1; anti-NAT1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous level of total NAT1 protein.
• Purity/Purification: Antibodies were purified by affinity purification using immunogen.
• Form/Format: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1.0 mg/ml (varies by lot)
• Sequence Length: 290

• Applicable Applications for anti-NAT1 antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Western blotting: 1:500 - 1:2000; Immunohistochemistry: 1:50 - 1:100
• Immunogen Type: Recombinant Protein
• Immunogen Description: Recombinant protein of human NAT1.
• Target Name: NAT1
• Preparation and Storage: Store at -20 degree C

Western Blot (WB)

(Western blot analysis of extracts of U937 cell line, using NAT1 antibody.)

Related Product Information for anti-NAT1 antibody

This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene.

Product Categories/Family for anti-NAT1 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 42741671
• NCBI GeneID: 9
• NCBI Accession #: NP_000653.3
• NCBI GenBank Nucleotide #: NM_000662.7
• UniProt Accession #: P18440; O15159; O15300; Q546N1; Q96TE9; A8K4E7
• Molecular Weight: 33,899 Da
• NCBI Official Full Name: arylamine N-acetyltransferase 1 isoform a
• NCBI Official Synonym Full Names: N-acetyltransferase 1 (arylamine N-acetyltransferase)
• NCBI Official Symbol: NAT1
• NCBI Official Synonym Symbols: AAC1; MNAT; NATI; NAT-1
• NCBI Protein Information: arylamine N-acetyltransferase 1
• UniProt Protein Name: Arylamine N-acetyltransferase 1
• Protein Family: Nucleobase-ascorbate transporter
• UniProt Gene Name: NAT1
• UniProt Synonym Gene Names: AAC1; MNAT; NAT-1
• UniProt Entry Name: ARY1_HUMAN

NCBI Description

This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

Uniprot Description

NAT1: Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens. Belongs to the arylamine N-acetyltransferase family.

Protein type: Acetyltransferase; Secondary Metabolites Metabolism - caffeine; EC 2.3.1.5; Xenobiotic Metabolism - drug metabolism - other enzymes

Chromosomal Location of Human Ortholog: 8p22

Cellular Component: cytosol

Molecular Function: arylamine N-acetyltransferase activity

Biological Process: xenobiotic metabolic process