Rabbit NANS Polyclonal Antibody | anti-NANS antibody
NANS
Gene Names
NANS; SAS; SEMDG; SEMDCG; HEL-S-100
Reactivity
HumanPredicted: Rat, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Purified By Antigen Affinity Column
Synonyms
NANS; Polyclonal Antibody; SAS; SEMDG; HEL-S-100; anti-NANS antibody
Host
Rabbit
Reactivity
Human
Predicted: Rat, Mouse
Predicted: Rat, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified By Antigen Affinity Column
Form/Format
Already dissolved in sterile H2O with 1% BSA and 0.02% NaN3 and 50% Glycerol.
Sequence Length
1181
Applicable Applications for anti-NANS antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:20,000-80,000
WB: 1:200-1,000
IHC: 1:100-500
WB: 1:200-1,000
IHC: 1:100-500
Immunogen
Recombinant fragment corresponding to 104-325aa of human NANS.
Cellular Localization
Cytoplasm, Cytosol, Extracellular Vesicular Exosome
Related Product Information for anti-NANS antibody
Sialic acid synthase
References
Lawrence SM, Huddleston KA, Pitts LR, et al. Cloning and expression of the human N-acetylneuraminic acid phosphate synthase gene with 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid biosynthetic ability. J Biol Chem. 275:17869-17877(2000)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
40KD
NCBI Official Full Name
Homo sapiens N-acetylneuraminic acid synthase, mRNA
NCBI Official Synonym Full Names
N-acetylneuraminate synthase
NCBI Official Symbol
NANS
NCBI Official Synonym Symbols
SAS; SEMDG; SEMDCG; HEL-S-100
NCBI Protein Information
sialic acid synthase
Protein Family
NCBI Description
This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively; however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant. [provided by RefSeq, Jul 2008]
Research Articles on NANS
Similar Products
Product Notes
The NANS (Catalog #AAA8560657) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NANS reacts with Human Predicted: Rat, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's NANS can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:20,000-80,000 WB: 1:200-1,000 IHC: 1:100-500. Researchers should empirically determine the suitability of the NANS for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NANS, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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