Rabbit anti-Human MYT1 Polyclonal Antibody | anti-MYT1 antibody

MYT1, NT (MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1, Myelin transcription factor 1, Myelin transcription factor I, Proteolipid protein-binding protein) (FITC)

Cat. Num. AAA6323597

• Gene Names: MYT1; MTF1; MYTI; NZF2; PLPB1; ZC2HC4A; C20orf36
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: MYT1; Polyclonal Antibody; NT (MYT1; KIAA0835; KIAA1050; MTF1; MYTI; PLPB1; Myelin transcription factor 1; Myelin transcription factor I; Proteolipid protein-binding protein) (FITC); Proteolipid protein-binding protein; anti-MYT1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-MYT1 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: MYT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MYT1.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(MYT1 Antibody (N-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the MYT1 antibody detected the MYT1 protein (arrow).)

Related Product Information for anti-MYT1 antibody

MYT1 is a member of a family of neural specific, zinc finger-containing DNA-binding proteins. The protein binds to the promoter regions of proteolipid proteins of the central nervous system and plays a role in the developing nervous system.

Product Categories/Family for anti-MYT1 antibody

Antibodies; Transcription Factors

References

Choi, H.S., et al. Mol. Cell. Biol. 29(8):2168-2180(2009). Vega, A., et al. Gynecol. Oncol. 112(1):210-214(2009). Vana, A.C., et al. Glia 55(7):687-697(2007). Nielsen, J.A., et al. Mol. Cell. Neurosci. 25(1):111-123(2004). Nakajima, H., et al. J. Biol. Chem. 278(28):25277-25280(2003).

NCBI and Uniprot Product Information

• NCBI GI #: 17975763
• NCBI GeneID: 4661
• NCBI Accession #: NP_004526.1
• NCBI GenBank Nucleotide #: NM_004535.2
• UniProt Accession #: Q01538; O94922; Q7Z5W2; Q9UPV2; E1P5H0; F5H7M8
• Molecular Weight: 125,075 Da
• NCBI Official Full Name: myelin transcription factor 1
• NCBI Official Synonym Full Names: myelin transcription factor 1
• NCBI Official Symbol: MYT1
• NCBI Official Synonym Symbols: MTF1; MYTI; NZF2; PLPB1; ZC2HC4A; C20orf36
• NCBI Protein Information: myelin transcription factor 1; myelin transcription factor I; proteolipid protein binding protein; proteolipid protein-binding protein; neural zinc finger transcription factor 2
• UniProt Protein Name: Myelin transcription factor 1
• Protein Family: Myelin transcription factor
• UniProt Gene Name: MYT1
• UniProt Synonym Gene Names: KIAA0835; KIAA1050; MTF1; MYTI; PLPB1; MyT1; MyTI
• UniProt Entry Name: MYT1_HUMAN

NCBI Description

The protein encoded by this gene is a member of a family of neural specific, zinc finger-containing DNA-binding proteins. The protein binds to the promoter regions of proteolipid proteins of the central nervous system and plays a role in the developing nervous system. [provided by RefSeq, Jul 2008]

Uniprot Description

PLPB1: Binds to the promoter regions of proteolipid proteins of the central nervous system. May play a role in the development of neurons and oligodendrogalia in the CNS. May regulate a critical transition point in oligodendrocyte lineage development by modulating oligodendrocyte progenitor proliferation relative to terminal differentiation and up-regulation of myelin gene transcription.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 20q13.33

Cellular Component: nucleoplasm; cytoplasm; nucleus

Molecular Function: zinc ion binding; transcription factor activity

Biological Process: nervous system development; regulation of transcription, DNA-dependent; transcription, DNA-dependent; cell differentiation