Rabbit anti-Human MYO6 Polyclonal Antibody | anti-MYO6 antibody
MYO6, CT (R1181) (MYO6, KIAA0389, Unconventional myosin-VI, Unconventional myosin-6) (AP)
ELISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
Western Blot (WB)
(MYO6 Antibody (C-term R1181) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the MYO6 antibody detected the MYO6 protein (arrow).)
Immunohistochemistry (IHC)
(MYO6 Antibody (C-term R1181) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MYO6 Antibody (C-term R1181) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunofluorescence (IF)
(Confocal immunofluorescent analysis of MYO6 Antibody (C-term R1181) with MCF-7 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).)
NCBI and Uniprot Product Information
Uniprot Description
MYO6: a molecular motor involved in intracellular vesicle and organelle transport. It is one of the so-called unconventional myosins.
Protein type: Motility/polarity/chemotaxis; Actin-binding; Motor
Chromosomal Location of Human Ortholog: 6q13
Cellular Component: Golgi apparatus; nuclear membrane; microvillus; lysosomal membrane; cytoplasmic membrane-bound vesicle; clathrin coated vesicle membrane; coated pit; DNA-directed RNA polymerase II, holoenzyme; cell cortex; clathrin-coated endocytic vesicle; cytosol; nucleoplasm; filamentous actin; ruffle; cell soma; membrane; perinuclear region of cytoplasm; endocytic vesicle; apical part of cell; axon; cytoplasm; unconventional myosin complex; plasma membrane; nucleus
Molecular Function: actin filament binding; calmodulin binding; minus-end directed microfilament motor activity; protein binding; motor activity; actin binding; ADP binding; ATP binding
Biological Process: response to drug; inner ear morphogenesis; DNA damage response, signal transduction by p53 class mediator; metabolic process; actin filament-based movement; regulation of synaptic plasticity; auditory receptor cell differentiation; regulation of secretion; locomotory behavior; endocytosis; synaptic transmission; intracellular protein transport; synaptogenesis; sensory perception of sound; glutamate secretion; dendrite development; positive regulation of transcription from RNA polymerase II promoter; protein targeting
Disease: Deafness, Autosomal Recessive 37; Deafness, Autosomal Dominant 22
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Product Notes
The MYO6 myo6 (Catalog #AAA6323462) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MYO6, CT (R1181) (MYO6, KIAA0389, Unconventional myosin-VI, Unconventional myosin-6) (AP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MYO6 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB). IHC: 1:50-100 ELISA: 1:1,000 WB: 1:100-500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the MYO6 myo6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MYO6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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