Western Blot (WB)
(MyD88 pAb tested by Western blot. MyD88 detection by Western blot. The analysis was performed using Jurkat whole-cell extract and MyD88 pAb at a 2 ug/ml dilution.)
Rat anti-Human MyD88 Polyclonal Antibody | anti-MyD88 antibody
MyD88 antibody (pAb)
Gene Names
MYD88; MYD88D
Reactivity
Human
Applications
Western Blot
Purity
Affinity Purified
Synonyms
MyD88; Polyclonal Antibody; MyD88 antibody (pAb); MYD88D; anti-MyD88 antibody
Host
Rat
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purified
Form/Format
PBS containing 0.02% sodium azide. Sodium azide is highly toxic.
Concentration
0.5ug/ul (varies by lot)
Applicable Applications for anti-MyD88 antibody
Western Blot (WB)
Application Notes
Applications Validated:
WB: 2-4ug/ml dilution
For optimal results, primary antibody incubations should be performed at room temperature. The addition of 0.1% Tween 20 to all blocking solutions may also reduce background.
WB: 2-4ug/ml dilution
For optimal results, primary antibody incubations should be performed at room temperature. The addition of 0.1% Tween 20 to all blocking solutions may also reduce background.
Immunogen
This MyD88 antibody was raised against a synthetic peptide corresponding to amino acid residues 233-248 of human MyD88.
Preparation and Storage
Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20 degree C for up to 2 years. Keep all reagents on ice when not in storage.1ug/ul
Western Blot (WB)
(MyD88 pAb tested by Western blot. MyD88 detection by Western blot. The analysis was performed using Jurkat whole-cell extract and MyD88 pAb at a 2 ug/ml dilution.)
Western Blot (WB)
(MyD88 pAb tested by Western blot. MyD88 detection by Western blot. The analysis was performed using Jurkat whole-cell extract and MyD88 pAb at a 2 ug/ml dilution.)
Related Product Information for anti-MyD88 antibody
Short Description: Our MyD88 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot; it has been shown to react with Human samples.
Background: MyD88 is an adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. MyD88 acts via IRAK1, IRAK2 and TRAF6, leading to NFkB (NFkB p50 & NFkB p65) activation, cytokine secretion and the inflammatory response. MyD88 increases IL-8 transcription, and may be involved in myeloid differentiation.
Background: MyD88 is an adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. MyD88 acts via IRAK1, IRAK2 and TRAF6, leading to NFkB (NFkB p50 & NFkB p65) activation, cytokine secretion and the inflammatory response. MyD88 increases IL-8 transcription, and may be involved in myeloid differentiation.
Product Categories/Family for anti-MyD88 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
34,097 Da
NCBI Official Full Name
myeloid differentiation primary response protein MyD88 isoform 2
NCBI Official Synonym Full Names
myeloid differentiation primary response 88
NCBI Official Symbol
MYD88
NCBI Official Synonym Symbols
MYD88D
NCBI Protein Information
myeloid differentiation primary response protein MyD88
UniProt Protein Name
Myeloid differentiation primary response protein MyD88
Protein Family
UniProt Gene Name
MYD88
UniProt Entry Name
MYD88_HUMAN
NCBI Description
This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
Research Articles on MyD88
Similar Products
Product Notes
The MyD88 myd88 (Catalog #AAA388676) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The MyD88 antibody (pAb) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MyD88 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications Validated: WB: 2-4ug/ml dilution For optimal results, primary antibody incubations should be performed at room temperature. The addition of 0.1% Tween 20 to all blocking solutions may also reduce background. Researchers should empirically determine the suitability of the MyD88 myd88 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MyD88, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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