Rabbit MXI1 Polyclonal Antibody | anti-MXI1 antibody
MXI1 Antibody
Gene Names
MXI1; MXI; MAD2; MXD2; bHLHc11
Reactivity
Human, Mouse, Rat
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
MXI1; Polyclonal Antibody; MXI1 Antibody; bHLHc11; Class C basic helix-loop-helix protein 11; MAD 2; MAD2; MAX dimerization protein 2; MAX interacting protein 1; Max interactor 1; Max related transcription factor; MAX-interacting protein 1; MGC43220; MXD 2; MXD2; MXI 1; MXI; mxi1; MXI1 protein; MXI1_HUMAN; Protein MXI1; anti-MXI1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
MXI1 Antibody detects endogenous levels of MXI1.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-MXI1 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human MXI1.
Conjugation
Unconjugated
Subunit Structure
Interacts with SMC3 (By similarity). Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX. Interacts with RNF17 (By similarity).
Tissue Specificity
High levels found in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle.
Function
Transcriptional repressor. MXI1 binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. MXI1 thus antagonizes MYC transcriptional activity by competing for MAX.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
26,062 Da
NCBI Official Full Name
max-interacting protein 1 isoform c
NCBI Official Synonym Full Names
MAX interactor 1, dimerization protein
NCBI Official Symbol
MXI1
NCBI Official Synonym Symbols
MXI; MAD2; MXD2; bHLHc11
NCBI Protein Information
max-interacting protein 1; MAX dimerization protein 2; Max-related transcription factor; class C basic helix-loop-helix protein 11
UniProt Protein Name
Max-interacting protein 1
Protein Family
UniProt Gene Name
MXI1
UniProt Synonym Gene Names
BHLHC11; Max interactor 1; bHLHc11
UniProt Entry Name
MXI1_HUMAN
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Product Notes
The MXI1 mxi1 (Catalog #AAA9630871) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MXI1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MXI1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the MXI1 mxi1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MXI1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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