Western Blot (WB)
(Anti-TNFSF18 rabbit polyclonal antibody at 1:500 dilution Lane A: Mouse brain tissue lysate Lane B: Mouse slpeen tissue lysate Lysates/proteins at 30 ug per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:20 kDa)
Rabbit anti-Mouse TNFSF18 Polyclonal Antibody | anti-TNFSF18 antibody
Anti-TNFSF18 Antibody, Rabbit Polyclonal
Gene Names
Tnfsf18; Gitrl
Reactivity
Mouse
Applications
Western Blot
Purity
Protein A & Antigen Affinity
Synonyms
TNFSF18; Polyclonal Antibody; Anti-TNFSF18 Antibody; Rabbit Polyclonal; TNFSF18 Antibody; Rabbit PAb; Antigen Affinity Purified; tumor necrosis factor (ligand) superfamily; member 18; Anti-Gitrl Antibody; anti-TNFSF18 antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Mouse TNFSF18
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-TNFSF18 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
A synthetic peptide corresponding to the N-terminus of the Mouse TNFSF18
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Mouse TNFSF18, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Western Blot (WB)
(Anti-TNFSF18 rabbit polyclonal antibody at 1:500 dilution Lane A: Mouse brain tissue lysate Lane B: Mouse slpeen tissue lysate Lysates/proteins at 30 ug per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:20 kDa)
Western Blot (WB)
(Anti-TNFSF18 rabbit polyclonal antibody at 1:500 dilution Lane A: Mouse brain tissue lysate Lane B: Mouse slpeen tissue lysate Lysates/proteins at 30 ug per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:20 kDa)
Related Product Information for anti-TNFSF18 antibody
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells.
Product Categories/Family for anti-TNFSF18 antibody
References
Liu Y, Tang X, Tian J, et al. Th17/Treg Cells Imbalance and GITRL Profile in Patients with Hashimoto's Thyroiditis. Nicot C, ed. International Journal of Molecular Sciences. 2014;15(12):21674-21686.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
19,732 Da
NCBI Official Full Name
Tumor necrosis factor ligand superfamily member 18
NCBI Official Synonym Full Names
tumor necrosis factor (ligand) superfamily, member 18
NCBI Official Symbol
Tnfsf18
NCBI Official Synonym Symbols
Gitrl
NCBI Protein Information
tumor necrosis factor ligand superfamily member 18; GITR ligand; glucocorticoid-induced TNF-related ligand; glucocorticoid-induced-tumor necrosis factor receptor ligand
UniProt Protein Name
Tumor necrosis factor ligand superfamily member 18
Protein Family
UniProt Gene Name
Tnfsf18
UniProt Synonym Gene Names
Gitrl; GITRL
UniProt Entry Name
TNF18_MOUSE
Uniprot Description
TNFSF18: Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T- cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Belongs to the tumor necrosis factor family.
Protein type: Membrane protein, integral; Cytokine; Apoptosis
Cellular Component: extracellular space; cell surface; membrane; plasma membrane; integral to membrane
Molecular Function: protein binding; cytokine activity; tumor necrosis factor receptor superfamily binding; tumor necrosis factor receptor binding
Biological Process: cell-cell signaling; tumor necrosis factor-mediated signaling pathway; immune system process; T cell proliferation during immune response; regulation of T cell proliferation; immune response; activation of NF-kappaB transcription factor
Research Articles on TNFSF18
Similar Products
Product Notes
The TNFSF18 tnfsf18 (Catalog #AAA8103735) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-TNFSF18 Antibody, Rabbit Polyclonal reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TNFSF18 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the TNFSF18 tnfsf18 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TNFSF18, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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