Rabbit anti-Mouse Multidrug resistance protein 3 Polyclonal Antibody | anti-Abcb4 antibody
Rabbit anti-mouse Multidrug resistance protein 3 polyclonal Antibody, Biotin conjugated
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
NCBI and Uniprot Product Information
Uniprot Description
ABCB4: a transporter that mediates ATP-dependent export of organic anions and drugs from the cytoplasm. Hydrolyzes ATP with low efficiency. Human ABCB4 is not capable of conferring drug resistance. Mediates the translocation of phosphatidylcholine across the canalicular membrane of the hepatocyte. Interacts with HAX1. Defects are the cause of gallstones, and progressive familial intrahepatic cholestasis 3, an autosomal recessive liver disorder that progresses to cirrhosis and liver failure before adulthood. Two alternatively spliced human isoforms have been described.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter, ABC family; Transporter; EC 3.6.3.44; Hydrolase
Cellular Component: apical plasma membrane; cytoplasm; cytoplasmic vesicle; Golgi membrane; integral to membrane; intercellular canaliculus; membrane; plasma membrane
Molecular Function: ATP binding; ATPase activity; ATPase activity, coupled to transmembrane movement of substances; hydrolase activity; nucleotide binding; phosphatidylcholine transmembrane transporter activity; xenobiotic-transporting ATPase activity
Biological Process: antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent; antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent; antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent; bile acid secretion; lipid homeostasis; lipid transport; multidrug transport; phospholipid translocation; positive regulation of antigen processing and presentation of peptide antigen via MHC class I; positive regulation of cholesterol transport; transmembrane transport; transport
Research Articles on Abcb4
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Product Notes
The Abcb4 abcb4 (Catalog #AAA1489060) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-mouse Multidrug resistance protein 3 polyclonal Antibody, Biotin conjugated reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Multidrug resistance protein 3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the Abcb4 abcb4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Multidrug resistance protein 3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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