Western Blot (WB)
(Host: RabbitTarget Name: MTSS1Sample Tissue: Human HT1080 Whole CellAntibody Dilution: 1.0ug/ml)
Rabbit anti-Human MTSS1 Polyclonal Antibody | anti-MTSS1 antibody
MTSS1 Antibody - middle region
Western Blot (WB)
(Host: RabbitTarget Name: MTSS1Sample Tissue: Human HT1080 Whole CellAntibody Dilution: 1.0ug/ml)
Western Blot (WB)
(Host: RabbitTarget Name: MTSS1Sample Tissue: Human HT1080 Whole CellAntibody Dilution: 1.0ug/ml)
NCBI and Uniprot Product Information
Uniprot Description
MTSS1: an intracellular protein that binds to actin and cortactin, and possesses tumor suppressor activity. Binds to the cytoplasmic domain of receptor protein tyrosine phosphatase delta. Senses and induces curved membranous curvatures important for cellular polarization, mobilization and endocytosis. May be related to cancer progression or tumor metastasis in a variety of organ sites. Its expression is down-regulated by MiR-135a. Downregulated in prostate cancer. Expressed in many tissues, including spleen, thymus, prostate, testis, uterus, colon, and peripheral blood. Belongs to the MTSS1 family. Three isoforms of the human protein are produced by alternative splicing.
Protein type: Tumor suppressor; Adaptor/scaffold; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 8p22
Cellular Component: ruffle; adherens junction; endocytic vesicle; cytoplasm; actin cytoskeleton
Molecular Function: actin monomer binding; actin filament binding; identical protein binding; protein binding; receptor binding
Biological Process: plasma membrane organization and biogenesis; in utero embryonic development; actin filament polymerization; microspike biogenesis; positive regulation of actin filament bundle formation; cell motility; cell adhesion; actin cytoskeleton organization and biogenesis; bone mineralization; transmembrane receptor protein tyrosine kinase signaling pathway; negative regulation of epithelial cell proliferation
Research Articles on MTSS1
Similar Products
Product Notes
The MTSS1 mtss1 (Catalog #AAA3220506) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MTSS1 Antibody - middle region reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MTSS1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the MTSS1 mtss1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: KDWAKPGPYD QPLVNTLQRR KEKREPDPNG GGPTTASGPP AAAEEAQRPR. It is sometimes possible for the material contained within the vial of "MTSS1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
