Western Blot (WB)
(Western blot analysis of lysate from human lung tissue lysate, using MTRF1 Antibody (Center). MBS9211339 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.)
Rabbit MTRF1 Polyclonal Antibody | anti-MTRF1 antibody
MTRF1 Antibody (Center)
Western Blot (WB)
(Western blot analysis of lysate from human lung tissue lysate, using MTRF1 Antibody (Center). MBS9211339 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.)
Western Blot (WB)
(Western blot analysis of lysate from human lung tissue lysate, using MTRF1 Antibody (Center). MBS9211339 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.)
silico methods to be a mitochondrial protein with similarity to the
peptide chain release factors (RFs) discovered in bacteria and
yeast. The peptide chain release factors direct the termination of
translation in response to the peptide chain termination codons.
Initially thought to have a role in the termination of mitochondria
protein synthesis, a recent publication found no mitochondrial
translation release functionality. Multiple alternatively spliced
transcript variants have been suggested by mRNA and EST data;
however, their full-length natures are not clear. [provided by
RefSeq].
Nozaki, Y., et al. Genes Cells 13(5):429-438(2008)
Soleimanpour-Lichaei, H.R., et al. Mol. Cell 27(5):745-757(2007)
Hansen, L.L., et al. Cytogenet. Cell Genet. 88 (1-2), 91-92 (2000) :
Zhang, Y., et al. Biochim. Biophys. Acta 1443 (1-2), 245-250 (1998) :
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene was determined by in silico methods to be a mitochondrial protein with similarity to the peptide chain release factors (RFs) discovered in bacteria and yeast. The peptide chain release factors direct the termination of translation in response to the peptide chain termination codons. Initially thought to have a role in the termination of mitochondria protein synthesis, a recent publication found no mitochondrial translation release functionality. Multiple alternatively spliced transcript variants have been suggested by mRNA and EST data; however, their full-length natures are not clear. [provided by RefSeq, Jul 2008]
Uniprot Description
MTRF1: Mitochondrial peptide chain release factor that directs the termination of translation in response to the peptide chain non-cognate termination stop codons AGG and AGA. Belongs to the prokaryotic/mitochondrial release factor family.
Protein type: Mitochondrial
Chromosomal Location of Human Ortholog: 13q14.1-q14.3
Cellular Component: mitochondrion
Molecular Function: translation release factor activity; translation release factor activity, codon specific
Biological Process: translational termination; regulation of translational termination
Research Articles on MTRF1
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Product Notes
The MTRF1 mtrf1 (Catalog #AAA9211339) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 232-259. The MTRF1 Antibody (Center) reacts with Human (Predicted Reactivity: Bovine, Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's MTRF1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the MTRF1 mtrf1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MTRF1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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