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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human liver using MBS7601646 (MTMR6 antibody) at dilution of 1:100)

Rabbit MTMR6 Polyclonal Antibody | anti-MTMR6 antibody

MTMR6 Rabbit Polyclonal

Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Synonyms
MTMR6; Polyclonal Antibody; MTMR6 Rabbit Polyclonal; anti-MTMR6 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Form/Format
Liquid
Sequence Length
621
Applicable Applications for anti-MTMR6 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Immunogen
Myotubularin related protein 6
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human liver using MBS7601646 (MTMR6 antibody) at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human liver using MBS7601646 (MTMR6 antibody) at dilution of 1:100)

Western Blot (WB)

(human heart tissue were subjected to SDS PAGE followed by western blot with MBS7601646 (MTMR6 antibody) at dilution of 1:500)

Western Blot (WB) (human heart tissue were subjected to SDS PAGE followed by western blot with MBS7601646 (MTMR6 antibody) at dilution of 1:500)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
63,743 Da
NCBI Official Full Name
myotubularin-related protein 6
NCBI Official Synonym Full Names
myotubularin related protein 6
NCBI Official Symbol
MTMR6
NCBI Protein Information
myotubularin-related protein 6
UniProt Protein Name
Myotubularin-related protein 6
UniProt Gene Name
MTMR6
UniProt Entry Name
MTMR6_HUMAN

Uniprot Description

MTMR6: Phosphatase that acts on lipids with a phosphoinositol headgroup. Acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol 3 phosphatase. Negatively regulates proliferation of reactivated CD4+ T-cells. Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Protein phosphatase, tyrosine (non-receptor); Phosphatase, lipid; EC 3.1.3.-; Cofactor and Vitamin Metabolism - riboflavin; Carbohydrate Metabolism - fructose and mannose; Cofactor and Vitamin Metabolism - thiamine

Chromosomal Location of Human Ortholog: 13q12

Cellular Component: cytoplasm; cytosol; nuclear envelope

Molecular Function: calcium-activated potassium channel activity; phosphatidylinositol-3-phosphatase activity; protein binding; protein serine/threonine phosphatase activity; protein tyrosine phosphatase activity

Biological Process: phosphatidylinositol biosynthetic process; phosphoinositide dephosphorylation; protein amino acid dephosphorylation

Research Articles on MTMR6

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Product Notes

The MTMR6 mtmr6 (Catalog #AAA7601646) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MTMR6 Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MTMR6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the MTMR6 mtmr6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MTMR6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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