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Goat MTMR1 Polyclonal Antibody | anti-MTMR1 antibody

Goat anti-MTMR1 (isoform 1) Antibody

Reactivity
Expected from sequence similarity: Human
Applications
ELISA
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Synonyms
MTMR1; Polyclonal Antibody; Goat anti-MTMR1 (isoform 1) Antibody; myotubularin related protein 1; myotubularin-related protein 1; MTMR1 antibody; myotubularin related protein 1 antibody; myotubularin-related protein 1 antibody; MTMR1 (isoform 1); anti-MTMR1 antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Expected from sequence similarity: Human
Clonality
Polyclonal
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (varies by lot)
Sequence
SSPSHSATSVHTSV
Sequence Length
665
Applicable Applications for anti-MTMR1 antibody
Peptide ELISA (EIA)
Application Notes
Peptide ELISA: Antibody detection limit dilution 1: 32000.
Western Blot: Preliminary experiments gave no signal but low background in Human Liver and Placenta lysates at up to 1ug/ml.
Immunogen
Peptide with sequence C-SSPSHSATSVHTSV, from the C Terminus of the protein sequence according to NP_003819.1.
Epitope
C Terminus
Note
Please note this will only recognise Human isoform 1 (NP_003819.1), not isoform 2 (NP_789746).
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
63,330 Da
NCBI Official Full Name
myotubularin-related protein 1 isoform 2
NCBI Official Synonym Full Names
myotubularin related protein 1
NCBI Official Symbol
MTMR1
NCBI Protein Information
myotubularin-related protein 1
UniProt Protein Name
Myotubularin-related protein 1
UniProt Gene Name
MTMR1
UniProt Entry Name
MTMR1_HUMAN

NCBI Description

This gene encodes a member of the myotubularin related family of proteins. Members of this family contain the consensus sequence for the active site of protein tyrosine phosphatases. Alternatively spliced variants have been described but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Uniprot Description

MTMR1: Lipid phosphatase that acts on phosphatidylinositol 3- phosphate and phosphatidylinositol (3,5)-bisphosphate. Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Phosphatase, lipid; Cofactor and Vitamin Metabolism - riboflavin; Carbohydrate Metabolism - fructose and mannose; EC 3.1.3.64; Motility/polarity/chemotaxis; Cofactor and Vitamin Metabolism - thiamine; Protein phosphatase, tyrosine (non-receptor)

Chromosomal Location of Human Ortholog: Xq28

Cellular Component: cytoplasm; cytosol; plasma membrane

Molecular Function: phosphatidylinositol-3-phosphatase activity; protein tyrosine phosphatase activity

Biological Process: phosphatidylinositol biosynthetic process; phosphoinositide dephosphorylation

Research Articles on MTMR1

Similar Products

Product Notes

The MTMR1 mtmr1 (Catalog #AAA420949) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-MTMR1 (isoform 1) Antibody reacts with Expected from sequence similarity: Human and may cross-react with other species as described in the data sheet. AAA Biotech's MTMR1 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA). Peptide ELISA: Antibody detection limit dilution 1: 32000. Western Blot: Preliminary experiments gave no signal but low background in Human Liver and Placenta lysates at up to 1ug/ml. Researchers should empirically determine the suitability of the MTMR1 mtmr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: SSPSHSATSV HTSV. It is sometimes possible for the material contained within the vial of "MTMR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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