Western Blot (WB)
(MTHFS Antibody (C-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the MTHFS antibody detected the MTHFS protein (arrow).)
Rabbit anti-Human, mouse MTHFS Polyclonal Antibody | anti-MTHFS antibody
MTHFS Antibody (C-term)
Gene Names
MTHFS; HsT19268
Reactivity
Human, mouse
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
MTHFS; Polyclonal Antibody; MTHFS Antibody (C-term); 5-formyltetrahydrofolate cyclo-ligase; 10-methenyl-tetrahydrofolate synthetase; Methenyl-THF synthetase; anti-MTHFS antibody
Host
Rabbit
Reactivity
Human, mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This MTHFS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-159 amino acids from the C-terminal region of human MTHFS.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
133-159
Sequence Length
179
Applicable Applications for anti-MTHFS antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(MTHFS Antibody (C-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the MTHFS antibody detected the MTHFS protein (arrow).)
Western Blot (WB)
(MTHFS Antibody (C-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the MTHFS antibody detected the MTHFS protein (arrow).)
Related Product Information for anti-MTHFS antibody
MTHFS contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids.
Product Categories/Family for anti-MTHFS antibody
References
Kelemen, L.E., et al. Cancer Epidemiol. Biomarkers Prev. 19(7):1822-1830(2010)
Hazra, A., et al. Cancer Causes Control 21(3):331-345(2010)
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
Wu, D., et al. Cancer Res. 69(18):7294-7301(2009)
Franke, B., et al. Birth Defects Res. Part A Clin. Mol. Teratol. 85(3):216-226(2009)
Hazra, A., et al. Cancer Causes Control 21(3):331-345(2010)
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
Wu, D., et al. Cancer Res. 69(18):7294-7301(2009)
Franke, B., et al. Birth Defects Res. Part A Clin. Mol. Teratol. 85(3):216-226(2009)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
23256
NCBI Official Full Name
5-formyltetrahydrofolate cyclo-ligase isoform b
NCBI Official Synonym Full Names
5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
NCBI Official Symbol
MTHFS
NCBI Official Synonym Symbols
HsT19268
NCBI Protein Information
5-formyltetrahydrofolate cyclo-ligase
UniProt Protein Name
5-formyltetrahydrofolate cyclo-ligase
UniProt Gene Name
MTHFS
UniProt Synonym Gene Names
MTHFS; Methenyl-THF synthetase
UniProt Entry Name
MTHFS_HUMAN
NCBI Description
The protein encoded by this gene is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, a precursor of reduced folates involved in 1-carbon metabolism. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
Uniprot Description
Contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. Catalyzes the irreversible conversion of 5-formyltetrahydrofolate (5-FTHF) to yield 5,10-methenyltetrahydrofolate.
Research Articles on MTHFS
Similar Products
Product Notes
The MTHFS mthfs (Catalog #AAA9207558) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 133-159. The MTHFS Antibody (C-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's MTHFS can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the MTHFS mthfs for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MTHFS, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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