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Western Blot (WB) (PID/MTA2 Antibody (C-term) western blot analysis in Hela cell line and mouse brain tissue lysates (35ug/lane).This demonstrates the PID/MTA2 antibody detected the PID/MTA2 protein (arrow).)

Rabbit anti-Human MTA2 Polyclonal Antibody | anti-MTA2 antibody

MTA2, CT (Metastasis-associated Protein MTA2, Metastasis-associated 1-like 1, MTA1-L1 Protein, p53 Target Protein In Deacetylase Complex, PID, MTA1L1) (MaxLight 550)

Gene Names
MTA2; PID; MTA1L1
Reactivity
Human
Applications
Western Blot
Purity
Purified by Ammonium Sulfate Precipitation.
Synonyms
MTA2; Polyclonal Antibody; CT (Metastasis-associated Protein MTA2; Metastasis-associated 1-like 1; MTA1-L1 Protein; p53 Target Protein In Deacetylase Complex; PID; MTA1L1) (MaxLight 550); anti-MTA2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human MTA2.
Purity/Purification
Purified by Ammonium Sulfate Precipitation.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight550.
Applicable Applications for anti-MTA2 antibody
Western Blot (WB), FLISA
Application Notes
WB: 1:50-1:100
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
Synthetic peptide selected from the C-terminal region of human MTA2 (KLH).
Conjugate
MaxLight550
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(PID/MTA2 Antibody (C-term) western blot analysis in Hela cell line and mouse brain tissue lysates (35ug/lane).This demonstrates the PID/MTA2 antibody detected the PID/MTA2 protein (arrow).)

Western Blot (WB) (PID/MTA2 Antibody (C-term) western blot analysis in Hela cell line and mouse brain tissue lysates (35ug/lane).This demonstrates the PID/MTA2 antibody detected the PID/MTA2 protein (arrow).)

Immunohistochemistry (IHC)

(Formalin-fixed and paraffin-embedded human brain tissue reacted with PID/MTA2 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (Formalin-fixed and paraffin-embedded human brain tissue reacted with PID/MTA2 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)

Flow Cytometry (FC/FACS)

(Flow cytometric analysis of hela cells using PID/MTA2 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Flow Cytometry (FC/FACS) (Flow cytometric analysis of hela cells using PID/MTA2 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Product Categories/Family for anti-MTA2 antibody
References
1. Cui, Y., Mol. Endocrinol. 20(9), 2020-2035 (2006).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
55,037 Da
NCBI Official Full Name
metastasis-associated protein MTA2
NCBI Official Synonym Full Names
metastasis associated 1 family, member 2
NCBI Official Symbol
MTA2
NCBI Official Synonym Symbols
PID; MTA1L1
NCBI Protein Information
metastasis-associated protein MTA2; MTA1-L1 protein; metastasis -associated gene 1-like 1; metastasis associated gene family, member 2; metastasis-associated 1-like 1; metastasis-associated protein 2; p53 target protein in deacetylase complex
UniProt Protein Name
Metastasis-associated protein MTA2
UniProt Gene Name
MTA2
UniProt Synonym Gene Names
MTA1L1; PID; MTA1-L1 protein
UniProt Entry Name
MTA2_HUMAN

Uniprot Description

MTA2: May be involved in the regulation of gene expression as repressor and activator. The repression might be related to covalent modification of histone proteins.

Protein type: Transcription factor; DNA-binding; Motility/polarity/chemotaxis; Nuclear receptor co-regulator; Deacetylase

Chromosomal Location of Human Ortholog: 11q12-q13.1

Cellular Component: nucleoplasm; transcription factor complex; protein complex; membrane; histone deacetylase complex; nuclear chromatin; NuRD complex

Molecular Function: protein binding; nucleosomal DNA binding; zinc ion binding; histone deacetylase activity; transcription factor activity

Biological Process: chromatin assembly or disassembly; establishment and/or maintenance of chromatin architecture; ATP-dependent chromatin remodeling; DNA methylation; positive regulation of transcription from RNA polymerase II promoter; histone deacetylation; negative regulation of transcription from RNA polymerase II promoter

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Product Notes

The MTA2 mta2 (Catalog #AAA6487994) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MTA2, CT (Metastasis-associated Protein MTA2, Metastasis-associated 1-like 1, MTA1-L1 Protein, p53 Target Protein In Deacetylase Complex, PID, MTA1L1) (MaxLight 550) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MTA2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:50-1:100 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the MTA2 mta2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MTA2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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