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Western Blot (WB) (Western Blot analysis of extracts of various cells, using MRPL39 antibody.)

Rabbit MRPL39 Polyclonal Antibody | anti-MRPL39 antibody

MRPL39 Polyclonal Antibody

Gene Names
MRPL39; L5mt; L39mt; MRPL5; RPML5; MRP-L5; PRED22; PRED66; MSTP003; C21orf92
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
MRPL39; Polyclonal Antibody; MRPL39 Polyclonal Antibody; 39S ribosomal protein L39; L39mt; MRP-L39; L5mt; MRP-L5; C21orf92; MRPL5; RPML5; MSTP003; PRED22; anti-MRPL39 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
MRPL39 polyclonal antibody detects endogenous levels of MRPL39 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
338
Applicable Applications for anti-MRPL39 antibody
Western Blot (WB)
Application Notes
WB: 1:1000-1:4000
Immunogen
Recombinant protein of human MRPL39.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot analysis of extracts of various cells, using MRPL39 antibody.)

Western Blot (WB) (Western Blot analysis of extracts of various cells, using MRPL39 antibody.)
Related Product Information for anti-MRPL39 antibody
MRP-L39 (mitochondrial ribosomal protein L39), also known as MRP-L5, L39mt or L5mt, is a 338 amino acid mitochondrial protein that exists as a component of the 39S ribosomal subunit and works in conjunction with other MRPs to mediate protein synthesis. MRP-L39 exists as two isoforms produced by alternative splicing. Isoform one of MRP-L39 is ubiquitously expressed while isoform two is specifically expressed in heart. The gene encoding MRP-L39 maps to chromosome 21, which makes up about 1.5% of the human genome. Chromosome 21 contains nearly 300 genes and 47 million base pairs. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 39kDa
NCBI Official Full Name
39S ribosomal protein L39, mitochondrial isoform a
NCBI Official Synonym Full Names
mitochondrial ribosomal protein L39
NCBI Official Symbol
MRPL39
NCBI Official Synonym Symbols
L5mt; L39mt; MRPL5; RPML5; MRP-L5; PRED22; PRED66; MSTP003; C21orf92
NCBI Protein Information
39S ribosomal protein L39, mitochondrial
UniProt Protein Name
39S ribosomal protein L39, mitochondrial
Protein Family
UniProt Gene Name
MRPL39
UniProt Synonym Gene Names
C21orf92; MRPL5; RPML5; L39mt; MRP-L39; L5mt; MRP-L5
UniProt Entry Name
RM39_HUMAN

NCBI Description

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Two transcript variants encoding distinct isoforms have been described. A pseudogene corresponding to this gene is found on chromosome 5q. [provided by RefSeq, Jul 2008]

Uniprot Description

MRPL39: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Translation; Mitochondrial; Ribosomal

Chromosomal Location of Human Ortholog: 21q21.3

Cellular Component: mitochondrial inner membrane; mitochondrial ribosome

Molecular Function: nucleotide binding

Biological Process: mitochondrial translation; organelle organization and biogenesis

Research Articles on MRPL39

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Product Notes

The MRPL39 mrpl39 (Catalog #AAA3008881) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MRPL39 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MRPL39 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:1000-1:4000. Researchers should empirically determine the suitability of the MRPL39 mrpl39 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MRPL39, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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