Rabbit anti-Human MPPE1 Polyclonal Antibody | anti-MPPE1 antibody
MPPE1, CT (MPPE1, PGAP5, Metallophosphoesterase 1, Post-GPI attachment to proteins factor 5)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
NCBI and Uniprot Product Information
Uniprot Description
MPPE1: Metallophosphoesterase required for transport of GPI- anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins. Belongs to the metallophosphoesterase superfamily. MPPE1 family. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; EC 3.1.-.-; Hydrolase; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 18p11.21
Cellular Component: nucleoplasm; Golgi apparatus; ER-Golgi intermediate compartment membrane; cis-Golgi network; integral to membrane; ER-Golgi intermediate compartment
Molecular Function: phosphoric diester hydrolase activity; manganese ion binding
Biological Process: ER to Golgi vesicle-mediated transport; GPI anchor biosynthetic process
Research Articles on MPPE1
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Product Notes
The MPPE1 mppe1 (Catalog #AAA6010590) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MPPE1, CT (MPPE1, PGAP5, Metallophosphoesterase 1, Post-GPI attachment to proteins factor 5) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MPPE1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500. Researchers should empirically determine the suitability of the MPPE1 mppe1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MPPE1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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