MOSC2 Antibody | anti-MOSC2 antibody

MOSC2 Antibody

Cat. Num. AAA8506054

• Gene Names: MARC2; MOSC2
• Synonyms: MOSC2; MOSC2 Antibody; anti-MOSC2 antibody

• Sequence Length: 1573

Testing Data

Testing Data #2

NCBI and Uniprot Product Information

• NCBI GI #: 16877189
• NCBI GeneID: 54996
• Molecular Weight: 29,103 Da
• NCBI Official Full Name: Homo sapiens MOCO sulphurase C-terminal domain containing 2, mRNA
• NCBI Official Synonym Full Names: mitochondrial amidoxime reducing component 2
• NCBI Official Symbol: MARC2
• NCBI Official Synonym Symbols: MOSC2
• NCBI Protein Information: mitochondrial amidoxime reducing component 2
• UniProt Protein Name: Mitochondrial amidoxime reducing component 2
• UniProt Gene Name: MARC2
• UniProt Synonym Gene Names: MOSC2; mARC2; MOSC domain-containing protein 2; Moco sulfurase C-terminal domain-containing protein 2

NCBI Description

The protein encoded by this gene is an enzyme found in the outer mitochondrial membrane that reduces N-hydroxylated substrates. The encoded protein uses molybdenum as a cofactor and cytochrome b5 type B and NADH cytochrome b5 reductase as accessory proteins. One type of substrate used is N-hydroxylated nucleotide base analogues, which can be toxic to a cell. Other substrates include N(omega)-hydroxy-L-arginine (NOHA) and amidoxime prodrugs, which are activated by the encoded enzyme. Multiple transcript variants encoding the different isoforms have been found for this gene. [provided by RefSeq, Sep 2016]

Uniprot Description

As a component of the benzamidoxime prodrug-converting complex required to reduce N-hydroxylated prodrugs, such as benzamidoxime. Also able to reduce N(omega)-hydroxy-L-arginine (NOHA) and N(omega)-hydroxy-N(delta)-methyl-L-arginine (NHAM) into L-arginine and N(delta)-methyl-L-arginine, respectively.