Western Blot (WB)
(Western Blot: Sample: Recombinant MCP1, Rat.)
Rabbit anti-Rat Monocyte Chemotactic Protein 1 (MCP1) Polyclonal Antibody | anti-MCP1 antibody
Polyclonal Antibody to Monocyte Chemotactic Protein 1 (MCP1)
MGHHHHHHSGSEF-QPDAVNA PLTCCYSFTG KMIPMSRLEN YKRITSSRCP KEAVVFVTKL KREICADPNK EWVQKYIRKL DQNQVRSETT VFYKIASTLR TSAPLNVNLT HKSEANASTL FSTTTSSTSV EVTSMTEN
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Western Blot (WB)
(Western Blot: Sample: Recombinant MCP1, Rat.)
Western Blot (WB)
(Western Blot: Sample: Recombinant MCP1, Rat.)
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin-embedded liver tissue))
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin-embedded liver tissue))
NCBI and Uniprot Product Information
NCBI Description
a monocyte chemoattractant protein [RGD, Feb 2006]
Uniprot Description
CCL13: Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenous pathogens. By IL1/interleukin-1 and TNF. Widely expressed. Found in small intestine, thymus, colon, lung, trachea, stomach and lymph node. Low levels seen in the pulmonary artery smooth muscle cells. Belongs to the intercrine beta (chemokine CC) family.
Protein type: Chemokine; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 10q26
Cellular Component: axon terminus; cell soma; cytoplasm; dendrite; endocytic vesicle; extracellular region; extracellular space; perikaryon; perinuclear region of cytoplasm; rough endoplasmic reticulum; synapse
Molecular Function: CCR2 chemokine receptor binding; chemokine activity; cytokine activity; G-protein coupled receptor binding; heparin binding
Biological Process: aging; astrocyte cell migration; cellular calcium ion homeostasis; cellular response to insulin stimulus; chemokinesis; chronic inflammatory response; cytokine-mediated signaling pathway; cytoskeleton organization; G-protein coupled receptor signaling pathway; glial cell migration; inflammatory response; leukocyte migration involved in inflammatory response; lipopolysaccharide-mediated signaling pathway; lymphocyte chemotaxis; macrophage chemotaxis; MAPK cascade; maternal process involved in female pregnancy; maternal process involved in parturition; monocyte chemotaxis; negative regulation of angiogenesis; negative regulation of neuron apoptosis; neutrophil chemotaxis; organ regeneration; positive regulation of cell adhesion; positive regulation of cell-cell adhesion; positive regulation of cellular extravasation; positive regulation of collagen biosynthetic process; positive regulation of endothelial cell proliferation; positive regulation of GTPase activity; positive regulation of leukocyte mediated cytotoxicity; positive regulation of leukocyte migration; positive regulation of nitric-oxide synthase biosynthetic process; positive regulation of synaptic transmission; positive regulation of T cell activation; positive regulation of tumor necrosis factor production; protein kinase B signaling; regulation of cell shape; response to activity; response to amino acid; response to antibiotic; response to drug; response to ethanol; response to gamma radiation; response to glucocorticoid stimulus; response to heat; response to hypoxia; response to lipopolysaccharide; response to mechanical stimulus; response to progesterone; response to vitamin B3; response to wounding; transforming growth factor beta receptor signaling pathway; vascular endothelial growth factor receptor signaling pathway
Research Articles on MCP1
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Product Notes
The MCP1 ccl2 (Catalog #AAA2004494) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Monocyte Chemotactic Protein 1 (MCP1) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Monocyte Chemotactic Protein 1 (MCP1) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the MCP1 ccl2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with a His-tag and its sequence is listed below. MGHHHHHHSG SEF-QPDAVN A PLTCCYSFTG KMIPMSRLEN YKRITSSRCP KEAVVFVTKL KREICADPNK EWVQKYIRKL DQNQVRSETT VFYKIASTLR TSAPLNVNLT HKSEANASTL FSTTTSSTSV EVTSMTEN. It is sometimes possible for the material contained within the vial of "Monocyte Chemotactic Protein 1 (MCP1), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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