Rabbit anti-Rat Monocarboxylate Transporter 3 Polyclonal Antibody | anti-SLC16A8 antibody

Monocarboxylate Transporter 3 (MCT3, MOT3)

Cat. Num. AAA614018

• Gene Names: SLC16A8; MCT3; REMP
• Reactivity: Rat
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: Monocarboxylate Transporter 3; Polyclonal Antibody; Monocarboxylate Transporter 3 (MCT3; MOT3); Anti -Monocarboxylate Transporter 3 (MCT3; anti-SLC16A8 antibody

• Host: Rabbit
• Reactivity: Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes rat Monocarboxylate Transporter 3 (MCT3). The immunogen shows no significant sequence homology with other MCT. Species sequence homology: Mouse.
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.4, 0.1% BSA, before the addition of glcerol to 40%.

• Applicable Applications for anti-SLC16A8 antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in ELISA and Western Blot.; Dilution: ELISA: 1:2500-1:25,000, using 50-100ng of control peptide/well; Western Blot (Chemiluminescence): 1-5ug/ml
• Immunogen: A 19 amino acid peptide sequence near the C-terminus of rat MCT3 (1).
• Preparation and Storage: For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Categories/Family for anti-SLC16A8 antibody

Antibodies; Abs to Monocarboxylate Transporter

NCBI and Uniprot Product Information

• NCBI GI #: 114796626
• NCBI GeneID: 23539
• NCBI Accession #: NP_037488.2
• NCBI GenBank Nucleotide #: NM_013356.2
• UniProt Accession #: O95907; Q9UBE2
• Molecular Weight: 52,319 Da
• NCBI Official Full Name: monocarboxylate transporter 3
• NCBI Official Synonym Full Names: solute carrier family 16, member 8 (monocarboxylic acid transporter 3)
• NCBI Official Symbol: SLC16A8
• NCBI Official Synonym Symbols: MCT3; REMP
• NCBI Protein Information: monocarboxylate transporter 3; MCT 3; OTTHUMP00000199351; solute carrier family 16 member 8; solute carrier 16 (monocarboxylic acid transporters), member 8
• UniProt Protein Name: Monocarboxylate transporter 3
• Protein Family: Monocarboxylate transporter
• UniProt Gene Name: SLC16A8
• UniProt Synonym Gene Names: MCT3
• UniProt Entry Name: MOT3_HUMAN

NCBI Description

SLC16A8 is a member of a family of proton-coupled monocarboxylate transporters that mediate lactate transport across cell membranes (Yoon et al., 1999 [PubMed 10493836]).[supplied by OMIM]

Uniprot Description

SLC16A8: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.

Protein type: Transporter; Transporter, SLC family; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 22q12.3-q13.2

Cellular Component: membrane; integral to plasma membrane; plasma membrane

Molecular Function: symporter activity; lactate transmembrane transporter activity; secondary active monocarboxylate transmembrane transporter activity

Biological Process: cellular metabolic process; lactate transport; blood coagulation; pyruvate metabolic process; transmembrane transport; leukocyte migration