Western Blot (WB)
(Western blotAll lanes: MOCS3 antibody at 2.1ug/mlLane 1 : A549 whole cell lysateLane 2 : HepG-2 whole cell lysateLane 3 : Jurkat whole cell lysateSecondaryGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 50 kDaObserved band size: 50 kDa)
Rabbit anti-Human MOCS3 Polyclonal Antibody | anti-MOCS3 antibody
MOCS3 Antibody
Western Blot (WB)
(Western blotAll lanes: MOCS3 antibody at 2.1ug/mlLane 1 : A549 whole cell lysateLane 2 : HepG-2 whole cell lysateLane 3 : Jurkat whole cell lysateSecondaryGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 50 kDaObserved band size: 50 kDa)
Western Blot (WB)
(Western blotAll lanes: MOCS3 antibody at 2.1ug/mlLane 1 : A549 whole cell lysateLane 2 : HepG-2 whole cell lysateLane 3 : Jurkat whole cell lysateSecondaryGoat polyclonal to Rabbit IgG at 1/10000 dilutionPredicted band size: 50 kDaObserved band size: 50 kDa)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human liver tissue using MBS7044832 at dilution 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human liver tissue using MBS7044832 at dilution 1:100)
NCBI and Uniprot Product Information
NCBI Description
Molybdenum cofactor (MoCo) is necessary for the function of all molybdoenzymes. The protein encoded by this gene adenylates and activates molybdopterin synthase, an enzyme required for biosynthesis of MoCo. This gene contains no introns. A pseudogene of this gene is present on chromosome 14. [provided by RefSeq, Nov 2012]
Uniprot Description
MOCS3: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.
Protein type: Ligase; EC 2.7.7.80; Transferase; EC 2.8.1.11
Chromosomal Location of Human Ortholog: 20q13.13
Cellular Component: cytosol
Molecular Function: nucleotidyltransferase activity; protein binding; sulfurtransferase activity; thiosulfate sulfurtransferase activity; URM1 activating enzyme activity
Biological Process: enzyme active site formation via L-cysteine persulfide; Mo-molybdopterin cofactor biosynthetic process; molybdopterin cofactor biosynthetic process; protein urmylation; tRNA wobble uridine modification
Research Articles on MOCS3
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Product Notes
The MOCS3 mocs3 (Catalog #AAA7044832) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MOCS3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MOCS3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the MOCS3 mocs3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MOCS3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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