Rabbit Mitochondrial Tumor Suppressor 1 Polyclonal Antibody | anti-MTUS1 antibody
Mitochondrial Tumor Suppressor 1 (MTUS1) Polyclonal Antibody
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Avoid repeated freeze/thaw cycles.
Store at 4°C for frequent use.
Aliquot and store at -20°C for 24 months.
Stability Test:
thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Western Blot (WB)
(Western Blot; Sample: Human K562 cell lysate;Primary Ab: 1ug/ml Rabbit Anti-Mouse MTUS1 AntibodySecond Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: MBS2086047 ))
Western Blot (WB)
(Western Blot; Sample: Mouse Cerebrum lysate;Primary Ab: 1ug/ml Rabbit Anti-Mouse MTUS1 AntibodySecond Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: MBS2086047 ))
NCBI and Uniprot Product Information
Uniprot Description
MTUS1: Cooperates with AGTR2 to inhibit ERK2 activation and cell proliferation. May be required for AGTR2 cell surface expression. Together with PTPN6, induces UBE2V2 expression upon angiotensin-II stimulation. Isoform 1 inhibits breast cancer cell proliferation, delays the progression of mitosis by prolonging metaphase and reduces tumor growth. Defects in MTUS1 may be a cause of hepatocellular carcinoma (HCC). Belongs to the MTUS1 family. 6 isoforms of the human protein are produced by alternative splicing.
Protein type: Mitochondrial; Tumor suppressor
Chromosomal Location of Human Ortholog: 8|8 A4
Cellular Component: cytoplasm; extracellular space; Golgi apparatus; membrane; microtubule cytoskeleton; mitochondrion; nucleolus; nucleus; plasma membrane
Biological Process: cell cycle; regulation of macrophage chemotaxis
Research Articles on MTUS1
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Product Notes
The MTUS1 mtus1 (Catalog #AAA2032354) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Mitochondrial Tumor Suppressor 1 (MTUS1) Polyclonal Antibody reacts with Mus musculus (Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's Mitochondrial Tumor Suppressor 1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB); Immunohistochemistry (IHC); Immunocytochemistry (ICC); Immunoprecipitation (IP). Western blotting: 0.5-2ug/mL Immunohistochemistry: 5-20ug/mL Immunocytochemistry: 5-20ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the MTUS1 mtus1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Mitochondrial Tumor Suppressor 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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