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Western Blot (WB) (Western Blot analysis of Mitochondrial ribosomal protein L11 in Jurkat, K562, lncap, hepg2 and hela cells in order using Mitochondrial ribosomal protein L11 Rabbit pAb at dilution 1/300)

Rabbit Mitochondrial ribosomal protein L11 Polyclonal Antibody | anti-MRPL11 antibody

Mitochondrial ribosomal protein L11 Rabbit pAb

Gene Names
MRPL11; L11MT; CGI-113; MRP-L11
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
Affinity purified
Synonyms
Mitochondrial ribosomal protein L11; Polyclonal Antibody; Mitochondrial ribosomal protein L11 Rabbit pAb; mitochondrial ribosomal protein L11; L11MT; CGI-113; MRP-L11; anti-MRPL11 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
0.2mg/ml (varies by lot)
Applicable Applications for anti-MRPL11 antibody
Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
WB: 1:500-1:2000
IHC-P: 1:50-1:200
Immunogen
Fusion protein of human MRPL11
Conjugation
Unconjugated
Modification
Unmodified
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Western Blot analysis of Mitochondrial ribosomal protein L11 in Jurkat, K562, lncap, hepg2 and hela cells in order using Mitochondrial ribosomal protein L11 Rabbit pAb at dilution 1/300)

Western Blot (WB) (Western Blot analysis of Mitochondrial ribosomal protein L11 in Jurkat, K562, lncap, hepg2 and hela cells in order using Mitochondrial ribosomal protein L11 Rabbit pAb at dilution 1/300)

Immunohistochemistry (IHC)

(Immunohistochemistry of Mitochondrial ribosomal protein L11 in paraffin-embedded Human lung cancer tissue using Mitochondrial ribosomal protein L11 Rabbit pAb at dilution 1/20. Predicted cell location: Cytoplasm)

Immunohistochemistry (IHC) (Immunohistochemistry of Mitochondrial ribosomal protein L11 in paraffin-embedded Human lung cancer tissue using Mitochondrial ribosomal protein L11 Rabbit pAb at dilution 1/20. Predicted cell location: Cytoplasm)
Related Product Information for anti-MRPL11 antibody
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
20,683 Da
NCBI Official Full Name
39S ribosomal protein L11, mitochondrial isoform a
NCBI Official Synonym Full Names
mitochondrial ribosomal protein L11
NCBI Official Symbol
MRPL11
NCBI Official Synonym Symbols
L11MT; CGI-113; MRP-L11
NCBI Protein Information
39S ribosomal protein L11, mitochondrial
UniProt Protein Name
39S ribosomal protein L11, mitochondrial
Protein Family
UniProt Gene Name
MRPL11
UniProt Synonym Gene Names
L11mt; MRP-L11
UniProt Entry Name
RM11_HUMAN

NCBI Description

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode different isoforms. Pseudogenes corresponding to this gene are found on chromosomes 5q and 12q. [provided by RefSeq, Jul 2008]

Uniprot Description

MRPL11: Belongs to the ribosomal protein L11P family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding; Mitochondrial

Chromosomal Location of Human Ortholog: 11q13.3

Cellular Component: mitochondrial inner membrane; mitochondrial ribosome

Molecular Function: protein binding; structural constituent of ribosome

Biological Process: translation; mitochondrial translation; organelle organization and biogenesis

Research Articles on MRPL11

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Product Notes

The MRPL11 mrpl11 (Catalog #AAA4758972) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Mitochondrial ribosomal protein L11 Rabbit pAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Mitochondrial ribosomal protein L11 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:500-1:2000 IHC-P: 1:50-1:200. Researchers should empirically determine the suitability of the MRPL11 mrpl11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Mitochondrial ribosomal protein L11, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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