Western Blot (WB)
(Western Blot analysis of various samples using Mineralocorticoid receptor Polyclonal Antibody at dilution of 1:600.)
Rabbit anti-Human Mineralocorticoid Receptor Polyclonal Antibody | anti-MLR antibody
Mineralocorticoid Receptor Polyclonal Antibody
Western Blot (WB)
(Western Blot analysis of various samples using Mineralocorticoid receptor Polyclonal Antibody at dilution of 1:600.)
Western Blot (WB)
(Western Blot analysis of various samples using Mineralocorticoid receptor Polyclonal Antibody at dilution of 1:600.)
NCBI and Uniprot Product Information
Observed: 107kDa
NCBI Description
This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Uniprot Description
Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
Research Articles on MLR
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Product Notes
The MLR nr3c2 (Catalog #AAA2556278) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Mineralocorticoid Receptor Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Mineralocorticoid Receptor can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the MLR nr3c2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Mineralocorticoid Receptor, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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