Western Blot (WB)
(MFN1 Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the MFN1 antibody detected the MFN1 protein (arrow).)
Rabbit anti-Human MFN1 Polyclonal Antibody | anti-MFN1 antibody
MFN1 Antibody (Center)
Western Blot (WB)
(MFN1 Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the MFN1 antibody detected the MFN1 protein (arrow).)
Western Blot (WB)
(MFN1 Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the MFN1 antibody detected the MFN1 protein (arrow).)
mitochondrial fusion. This protein and mitofusin 2 are homologs of
the Drosophila protein fuzzy onion (Fzo). They are mitochondrial
membrane proteins that interact with each other to facilitate
mitochondrial targeting.
Park, Y.Y., et al. J. Cell. Sci. 123 (PT 4), 619-626 (2010) :
Onoguchi, K., et al. PLoS Pathog. 6 (7), E1001012 (2010) :
Waxman, A.B., et al. Am. J. Respir. Cell Mol. Biol. 41(4):385-396(2009)
Wolf, C., et al. BMC Med. Genet. 10, 91 (2009) :
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting. [provided by RefSeq, Jul 2008]
Uniprot Description
MFN1: Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks. Belongs to the mitofusin family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Hydrolase; Mitochondrial; Membrane protein, integral; Membrane protein, multi-pass; EC 3.6.5.-
Chromosomal Location of Human Ortholog: 3q26.33
Cellular Component: mitochondrial outer membrane; integral to membrane
Molecular Function: GTPase activity; protein binding; GTP binding
Biological Process: mitochondrial fusion; metabolic process
Research Articles on MFN1
Similar Products
Product Notes
The MFN1 mfn1 (Catalog #AAA9212338) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 353-381. The MFN1 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MFN1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the MFN1 mfn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MFN1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
