Western Blot (WB)
(Western blot analysis of anti-MARS2 Antibody (C-term) (MBS9210873) in mouse testis tissue lysates (35ug/lane). MARS2(arrow) was detected using the purified Pab.)
Rabbit anti-Human Methionyl tRNA Synthetase Polyclonal Antibody | anti-MARS2 antibody
Methionyl tRNA Synthetase Antibody (C-term)
Western Blot (WB)
(Western blot analysis of anti-MARS2 Antibody (C-term) (MBS9210873) in mouse testis tissue lysates (35ug/lane). MARS2(arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of anti-MARS2 Antibody (C-term) (MBS9210873) in mouse testis tissue lysates (35ug/lane). MARS2(arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with MARS2 antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with MARS2 antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
ATP + L-methionine + tRNAMet <--> AMP + diphosphate + L-methionyl-tRNAMet
The 3 substrates of this enzyme are ATP, L-methionine, and tRNA(Met), whereas its 3 products are AMP, diphosphate, and L-methionyl-tRNA(Met).
This enzyme participates in 3 metabolic pathways: methionine metabolism, selenoamino acid metabolism, and aminoacyl-trna biosynthesis.
NCBI and Uniprot Product Information
NCBI Description
This gene produces a mitochondrial methionyl-tRNA synthetase protein that is encoded by the nuclear genome and imported to the mitochondrion. This protein likely functions as a monomer and is predicted to localize to the mitochondrial matrix. Mutations in this gene are associated with the autosomal recessive neurodegenerative disease spastic ataxia-3 (SPAX3). [provided by RefSeq, Apr 2014]
Uniprot Description
MARS2: Belongs to the class-I aminoacyl-tRNA synthetase family.
Protein type: EC 6.1.1.10; Ligase; Other Amino Acids Metabolism - selenoamino acid; Mitochondrial
Chromosomal Location of Human Ortholog: 2q33.1
Cellular Component: mitochondrial matrix; cytosol
Molecular Function: methionine-tRNA ligase activity; ATP binding
Biological Process: tRNA aminoacylation for protein translation; methionyl-tRNA aminoacylation; gene expression
Disease: Combined Oxidative Phosphorylation Deficiency 25; Spastic Ataxia 3, Autosomal Recessive
Research Articles on MARS2
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Product Notes
The MARS2 mars2 (Catalog #AAA9210873) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 564-593. The Methionyl tRNA Synthetase Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Methionyl tRNA Synthetase can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the MARS2 mars2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Methionyl tRNA Synthetase, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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