Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human colon cancer using at dilution of 1:100.)
Rabbit anti-Human Metalloproteinase inhibitor 4 Polyclonal Antibody | anti-TIMP4 antibody
Metalloproteinase inhibitor 4 Polyclonal Antibody
Reactivity
Human
Applications
Immunohistochemistry
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Synonyms
Metalloproteinase inhibitor 4; Polyclonal Antibody; Metalloproteinase inhibitor 4 Polyclonal Antibody; Tissue inhibitor of metalloproteinases 4; TIMP4; anti-TIMP4 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total Metalloproteinase inhibitor 4 polyclonal antibody.
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation purified
Form/Format
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
224
Applicable Applications for anti-TIMP4 antibody
Immunohistochemistry (IHC)
Application Notes
Immunohistochemistry: 1:20 - 1:200
Immunogen
Recombinant Human Metalloproteinase inhibitor 4 protein
Immunogen Type
Protein
Preparation and Storage
Store at -20 degree C
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human colon cancer using at dilution of 1:100.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human colon cancer using at dilution of 1:100.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human kidney using at dilution of 1:100.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human kidney using at dilution of 1:100.)
Related Product Information for anti-TIMP4 antibody
Complexes with metalloproteinases and irreversibly inactivates them by binding to their catalytic zinc cofactor.Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9.
Product Categories/Family for anti-TIMP4 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
25,503 Da
NCBI Official Full Name
metalloproteinase inhibitor 4
NCBI Official Synonym Full Names
TIMP metallopeptidase inhibitor 4
NCBI Official Symbol
TIMP4
NCBI Protein Information
metalloproteinase inhibitor 4
UniProt Protein Name
Metalloproteinase inhibitor 4
Protein Family
UniProt Gene Name
TIMP4
UniProt Synonym Gene Names
TIMP-4
UniProt Entry Name
TIMP4_HUMAN
Uniprot Description
TIMP4: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP- 9. Belongs to the protease inhibitor I35 (TIMP) family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 3p25
Cellular Component: extracellular space; proteinaceous extracellular matrix
Molecular Function: metalloendopeptidase inhibitor activity; protease binding
Biological Process: negative regulation of catalytic activity; negative regulation of membrane protein ectodomain proteolysis; response to organic substance
Similar Products
Product Notes
The TIMP4 timp4 (Catalog #AAA9416034) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Metalloproteinase inhibitor 4 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Metalloproteinase inhibitor 4 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Immunohistochemistry: 1:20 - 1:200. Researchers should empirically determine the suitability of the TIMP4 timp4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Metalloproteinase inhibitor 4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
