Western Blot (WB)
(Western Blot analysis of 1) K562, 2) AD293T cells with Phospho-MEF-2D (Ser444) Polyclonal Antibody at dilution of 1:500)
Rabbit MEF-2D Polyclonal Antibody | anti-MEF-2D antibody
Phospho-MEF-2D (Ser444) Polyclonal Antibody
IHC: 1:100-1:300
ELISA: 1:10000
Western Blot (WB)
(Western Blot analysis of 1) K562, 2) AD293T cells with Phospho-MEF-2D (Ser444) Polyclonal Antibody at dilution of 1:500)
Western Blot (WB)
(Western Blot analysis of 1) K562, 2) AD293T cells with Phospho-MEF-2D (Ser444) Polyclonal Antibody at dilution of 1:500)
NCBI and Uniprot Product Information
Observed Molecular Weight: 55kDa
NCBI Description
This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
Uniprot Description
MEF2D: transcription factor which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. May be involved in muscle-specific and/or growth factor-related transcription. Six splice-variant isoforms have been described.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 1q22
Cellular Component: cytoplasm; intracellular membrane-bound organelle; nucleoplasm; nucleus
Molecular Function: activating transcription factor binding; DNA binding transcription factor activity; histone deacetylase binding; protein binding; protein heterodimerization activity; protein homodimerization activity
Biological Process: adult heart development; apoptosis; chondrocyte differentiation; endochondral ossification; muscle organ development; nervous system development; osteoblast differentiation; positive regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter
Research Articles on MEF-2D
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Product Notes
The MEF-2D mef2d (Catalog #AAA2548824) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Phospho-MEF-2D (Ser444) Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MEF-2D can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA). WB: 1:500-1:2000 IHC: 1:100-1:300 ELISA: 1:10000. Researchers should empirically determine the suitability of the MEF-2D mef2d for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MEF-2D, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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